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We report a 52\u2010year\u2010old woman with stable bilateral gluteal calcifications after long\u2010term subcutaneous interferon\u2010\u03b2\u20101b therapy. Findings were most consistent with probable dystrophic calcinosis cutis secondary to chronic repeated injection\u2010site trauma.<\/jats:p>","DOI":"10.1002\/ccr3.72931","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T03:56:02Z","timestamp":1781495762000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["When Treatment Turns to Stone: Injection\u2010Site Calcinosis Associated With Interferon\u2010\u03b2 in Multiple Sclerosis: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Anna","family":"Walter","sequence":"first","affiliation":[{"name":"REHAB Basel, Clinic for Neurorehabilitation and Paraplegiology  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7581-2172","authenticated-orcid":false,"given":"Adam","family":"Bott","sequence":"additional","affiliation":[{"name":"REHAB Basel, Clinic for Neurorehabilitation and Paraplegiology  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Kiechle","sequence":"additional","affiliation":[{"name":"REHAB Basel, Clinic for Neurorehabilitation and Paraplegiology  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margret","family":"Hund\u2010Georgiadis","sequence":"additional","affiliation":[{"name":"REHAB Basel, Clinic for Neurorehabilitation and Paraplegiology  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,14]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.26858"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-021-00822-z"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2023.2248391"},{"issue":"4","key":"e_1_2_13_5_1","first-page":"214","article-title":"Adverse Side Effects of Glatiramer Acetate and Interferon Beta: Systematic Review","volume":"22","author":"Rastkar M.","year":"2023","journal-title":"Current Journal of Neurology"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.8.1622"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.08.038"},{"issue":"3","key":"e_1_2_13_8_1","first-page":"346","article-title":"Heterotopic Ossification and Dystrophic Calcification: A Comprehensive Review","volume":"43","author":"Shehab D.","year":"2002","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_13_9_1","article-title":"Adverse Effects of Immunotherapies for Multiple Sclerosis: A Network Meta\u2010Analysis","volume":"11","author":"Tramacere I.","year":"2023","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.139943"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.12788\/cutis.0586"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.72931","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:19:53Z","timestamp":1784305193000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.72931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/ccr3.72931"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.72931","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2026-05-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72931"}}