{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:05:16Z","timestamp":1784307916877,"version":"3.55.0"},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Cholestasis beyond infancy is uncommon and presents a diagnostic challenge. We report an 11\u2010year\u2010old girl presenting with severe pruritus followed by jaundice and a cholestatic biochemical profile with normal gamma\u2010glutamyl transferase levels. Extensive evaluation excluded infectious, autoimmune, metabolic, and obstructive causes. Liver biopsy demonstrated bland cholestasis with preserved hepatic architecture. The patient showed complete clinical and biochemical recovery following supportive therapy with ursodeoxycholic acid. Although this represents a first documented episode, the findings are most consistent with a benign recurrent intrahepatic cholestasis\u2013like phenotype. This case highlights the importance of considering inherited cholestatic disorders in older children with unexplained GGT\u2010normal cholestasis.<\/jats:p>","DOI":"10.1002\/ccr3.72950","type":"journal-article","created":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T05:27:09Z","timestamp":1781328429000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>GGT<\/scp>\n                    \u2010Normal Cholestasis in an Older Child: A Suspected Case of Benign Recurrent Intrahepatic Cholestasis From Syria"],"prefix":"10.1002","volume":"14","author":[{"given":"Ahmad","family":"Hosiian","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Tartous National Children's Hospital  Tartous Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balsam","family":"Aldali","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Tartous National Children's Hospital  Tartous Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihan","family":"Jendi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Tartous National Children's Hospital  Tartous Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6034-3721","authenticated-orcid":false,"given":"Mostafa","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Tartous University  Tartous Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Naamah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Latakia University  Latakia Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Amhanna","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Tartous National Children's Hospital  Tartous Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Moustafa","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Tartous National Children's Hospital  Tartous Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-019-0132-z"},{"issue":"3","key":"e_1_2_13_3_1","first-page":"621","article-title":"Cholestatic Liver Disease in Children","volume":"64","author":"Kamath B. 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