{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:25:22Z","timestamp":1787120722263,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We describe the case of a 44\u2010year\u2010old female with a history significant for only hypertension who presented to the emergency department with symptoms of aphasia and difficulty concentrating, persisting for six hours. Work\u2010up revealed evidence of a multifocal infarct suggestive of embolic etiology, along with evidence of a large 6.0 \u00d7\u20096.0 ascending thoracic artery and simultaneous aneurysm of the transverse arch. The patient subsequently underwent open surgical repair with placement of a Dacron graft, which she tolerated well without complications. Surgical pathology was positive for granulomatous inflammation suggestive of autoimmune or infectious etiology, and the patient was readmitted post\u2010surgical discharge for an extensive work\u2010up, which was found to be negative. A new diagnosis of Takayasu arteritis (TA) was made. During her subsequent hospitalization, she developed an episode of unstable atrial fibrillation with rapid ventricular response and acute hypotension requiring medical ICU observation. She was started on high\u2010dose steroids, trimethoprim\u2010sulfamethoxazole prophylaxis, and amiodarone with a positive clinical response. She underwent a cardiac MRI to evaluate for evidence of myocardial infiltration, which was determined to be normal. The development of atrial fibrillation was considered a postoperative complication, and amiodarone was discontinued at eight weeks. The patient received a gradual steroid taper with initiation of daily low\u2010dose prednisone and methotrexate and made a full recovery.<\/jats:p>","DOI":"10.1002\/ccr3.72978","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T05:44:23Z","timestamp":1782452663000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Atypical Case of Takayasu Aortitis Presenting as Embolic Stroke With Concomitant Massive Thoracic Artery Aneurysm"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9741-1954","authenticated-orcid":false,"given":"J. Curran","family":"Henson","sequence":"first","affiliation":[{"name":"Department of Internal Medicine University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan H.","family":"Myers","sequence":"additional","affiliation":[{"name":"College of Medicine University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Macy","family":"Cummins","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyur","family":"Vyas","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lowry","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease University of Arkansas for Medical Sciences  Little Rock Arkansas 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Case Report of Takayasu's Arteritis With Cerebral Infarction as Initial Presentation","volume":"14","author":"Memon T.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.24.1.35"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7412"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X241241190"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fstro.2024.1481940"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reuma.2021.11.003"},{"key":"e_1_2_11_21_1","first-page":"A17857","article-title":"Abstract 17857: Clinical Outcomes in Patients With Takayasu's Arteritis: Retrospective Analysis From National Inpatient Sample Database","volume":"130","author":"Garg 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