{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:25:33Z","timestamp":1787120733837,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune, demyelinating disorder of the central nervous system. Clinical manifestations include optic neuritis, longitudinally extensive transverse myelitis (LETM) involving three or more vertebral segments, and, in most cases, seropositivity for anti\u2010aquaporin\u20104 antibodies (AQP4\u2010IgG). Although longitudinally extensive transverse myelitis (LETM) is a hallmark feature of NMOSD, it is not pathognomonic and may occur in a variety of infectious, metabolic, neoplastic, and autoimmune conditions, including systemic lupus erythematosus (SLE). Here we report the case of a female patient who presented with severe tetraparesis, secondary to transverse myelitis. Serological evaluation revealed positivity for anti\u2010AQP4 antibodies, anti\u2010dsDNA antibodies, and ENA antibodies, leading to the simultaneous diagnosis of NMOSD and SLE. Nevertheless, it remained uncertain whether the transverse myelitis represented a manifestation of NMOSD or neurological involvement of SLE.<\/jats:p>","DOI":"10.1002\/ccr3.73003","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:41:27Z","timestamp":1782186087000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Longitudinal Extensive Transversal Myelitis in Patient With Neuromyelitis Optica Spectrum Disorder and Systemic Lupus Erythematosus"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9719-0178","authenticated-orcid":false,"given":"Nikolina","family":"Pravdic","sequence":"first","affiliation":[{"name":"Clinic of Neurology University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"},{"name":"School of Medicine, University of Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9556-9091","authenticated-orcid":false,"given":"Marijana","family":"Goluza","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasa","family":"Pejanovic Skobic","sequence":"additional","affiliation":[{"name":"Clinic of Neurology University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"},{"name":"School of Medicine, University of Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davor","family":"Batinic","sequence":"additional","affiliation":[{"name":"Clinic of Neurology University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Zovko","sequence":"additional","affiliation":[{"name":"Department of Imunology and Reumathology University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Zovko","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Mostar  Mostar Bosnia and Herzegovina"},{"name":"Department of Lung Diseases University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Ivankovic","sequence":"additional","affiliation":[{"name":"Clinic of Neurology University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge","family":"Klupka Saric","sequence":"additional","affiliation":[{"name":"Clinic of Neurology University Clinical Hospital Mostar  Mostar Bosnia and Herzegovina"},{"name":"School of Medicine, University of Mostar  Mostar Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.29271\/jcpsp.2022.11.1498"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.31138\/mjr.20230808.tc"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-022-03734-8"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/20009666.2021.1915533"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.5041\/RMMJ.10429"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.8818"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.9063"},{"key":"e_1_2_10_9_1","article-title":"Autoimmune Myelitis and Myocarditis in a Patient With Anti\u2010Aquaporin\u20104, Antinuclear, and Antiphospholipid Autoantibodies: The Neuromyelitis Optica\u2010Systemic Lupus Erythematosus (NMO\u2010SLE) Overlap Syndrome","volume":"14","author":"Mader E. 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