{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:13Z","timestamp":1786977373660,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T00:00:00Z","timestamp":1683158400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Key Clinical Message<\/jats:title>\n                    <jats:p>Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many clinical features in common and may coexist in the same patient. Visceral leishmaniasis should be promptly ruled out in patients coming from endemic areas before starting immunosuppressive therapy for hemophagocytic lymphohistiocytosis. The mainstay treatment, in this case, is anti\u2010leishmania medications preferably liposomal amphotericin\u2010B.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.7309","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T00:28:57Z","timestamp":1683246537000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Visceral leishmaniasis complicated by hemophagocytic lymphohistiocytosis: A case report from a nonendemic area"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8323-1303","authenticated-orcid":false,"given":"Anwar I.","family":"Joudeh","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Al\u2010Khor Hospital Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussein A.","family":"Elsiddig\u00a0Awadelkarim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Al\u2010Khor Hospital Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadshah Isam","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hamad General Hospital Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud Salm","family":"Elayana","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hamad General Hospital Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina Sameh","family":"Soliman","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliaa","family":"Amer","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musaed","family":"Alsamawi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases Division, Al\u2010Khor Hospital Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(14)61682-2"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7357.176"},{"key":"e_1_2_13_4_1","unstructured":"World Health Organization. Leishmaniasis in high\u2010burden countries: an epidemiological update based on data reported in 2014. Who.int.https:\/\/www.who.int\/publications\/i\/item\/who\u2010wer9122. Published 2016."},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.11.014"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-01-0172"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/inf.0000000000000916"},{"key":"e_1_2_13_8_1","first-page":"696","volume-title":"\u201cLeishmaniasis,\u201d in Tropical infectious diseases: Principles, pathogens, and Practice","author":"Guerrant RL","year":"2011"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e31802fe858"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu102"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw742"},{"key":"e_1_2_13_12_1","unstructured":"BernC.Visceral leishmaniasis: clinical manifestations and diagnosis. UpToDate.https:\/\/www.uptodate.com\/contents\/visceral\u2010leishmaniasis\u2010clinical\u2010manifestations\u2010and\u2010diagnosisPublished February 16 2022. Accessed October 23 2022."},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.03.047"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2008.02.013"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199223040-00004"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/10611869308996089"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T04:45:57Z","timestamp":1692420357000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/ccr3.7309"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7309","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"2022-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7309"}}