{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:25:32Z","timestamp":1787120732018,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Ulnar neuropathy (UN) is the second most common entrapment neuropathy, typically resulting from trauma, fractures, compression, dislocations, repetitive elbow movements, or congenital malformations secondary to previous injuries. However, it may also arise as a complication of substance abuse. We report the case of a 45\u2010year\u2010old male with bilateral ulnar neuropathy secondary to 22\u2009years of intravenous pentazocine (Sosegon) abuse, highlighting repeated local tissue injury and fibrosis as potential pathogenic factors. The patient presented with progressive swelling, numbness, and pain in both upper extremities, along with a bilateral flexion contracture of the left fourth and fifth digits. Nerve conduction studies (NCS) revealed severe left ulnar neuropathy at the elbow distal to the branch of the flexor carpi ulnaris, and moderate\u2010to\u2010severe right ulnar neuropathy at the elbow proximal to the same branch. Needle electromyography (EMG) demonstrated significant denervation in muscles innervated by the ulnar nerve. After preoperative evaluation, the patient underwent successful ulnar nerve transposition followed by physiotherapy, resulting in symptomatic improvement at six\u2010month follow\u2010up. This case highlights chronic pentazocine abuse as a rare but significant cause of bilateral ulnar neuropathy, likely due to repeated local trauma and fibrosis. Early recognition and a multidisciplinary management strategy involving neurosurgery, addiction medicine, and physiotherapy to address both the neurological sequelae and the underlying substance abuse are essential to optimizing long\u2010term functional and clinical outcomes.<\/jats:p>","DOI":"10.1002\/ccr3.73124","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T04:02:07Z","timestamp":1784520127000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral Ulnar Neuropathy Secondary to Chronic Pentazocine Injections: A Rare Neurological Sequela of Substance Abuse"],"prefix":"10.1002","volume":"14","author":[{"given":"Malaika","family":"Khan","sequence":"first","affiliation":[{"name":"Khyber Medical College  Peshawar KPK Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samra","family":"Aleem","sequence":"additional","affiliation":[{"name":"Khyber Medical College  Peshawar KPK Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Taha","sequence":"additional","affiliation":[{"name":"Khyber Medical College  Peshawar KPK Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malik W. Z.","family":"Khan","sequence":"additional","affiliation":[{"name":"Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajjad","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8208-0689","authenticated-orcid":false,"given":"Kamil Ahmad","family":"Kamil","sequence":"additional","affiliation":[{"name":"Nasrat Bashir Curative Hospital  Kandahar Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3352"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26183"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1558944718762566"},{"issue":"3","key":"e_1_2_13_5_1","article-title":"Osborne's Ligament: A Review of Its History, Anatomy, and Surgical Importance","volume":"9","author":"Granger A.","year":"2017","journal-title":"Cureus"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(86)80110-1"},{"issue":"3","key":"e_1_2_13_7_1","first-page":"301","article-title":"Compression Neuropathy of the Cubital Nerve at the Elbow","volume":"58","author":"Rombouts J. 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