{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:25:38Z","timestamp":1787120738601,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Desmoid\u2010type fibromatosis is a rare, non\u2010metastatic fibroblastic neoplasm that may cause major morbidity through locally infiltrative growth. Spinal involvement with vertebral destruction and neurological deficit is particularly uncommon and may mimic malignant spindle\u2010cell or primary osseous tumors. We report a 59\u2010year\u2010old woman with severe low back pain, progressive right lower\u2010limb weakness, sensory loss, swelling, and functional decline. Imaging showed a markedly enlarging right retroperitoneal\u2010pelvic mass with invasion and partial destruction of the L4\u2013L5 vertebral bodies. Although initially diagnosed as spindle cell sarcoma, histopathology, strong nuclear \u03b2\u2010catenin positivity, and CTNNB1 mutation analysis confirmed desmoid\u2010type fibromatosis. A pathogenic APC variant was also detected, raising the need to consider familial adenomatous polyposis evaluation. The patient underwent posterior decompression and long\u2010segment stabilization for neural compromise and spinal instability. This case highlights the severe local morbidity possible despite non\u2010metastatic histology.<\/jats:p>","DOI":"10.1002\/ccr3.73181","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:02:38Z","timestamp":1784264558000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Locally Aggressive Desmoid Tumor With\n                    <scp>L4<\/scp>\n                    \u2013\n                    <scp>L5<\/scp>\n                    Vertebral Invasion and Progressive Neurological Deficit: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Ghada A.","family":"AlAnsari","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, King Fahad University Hospital Imam Abdulrahman Bin Faisal University  Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Alanzi","sequence":"additional","affiliation":[{"name":"Anaesthesia and Pain Management King Hamad University Hospital  Al Sayh Bahrain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0724-7140","authenticated-orcid":false,"given":"Dawood","family":"Alatefi","sequence":"additional","affiliation":[{"name":"Yemeni\u2010Syrian Medical Center  Ja'ar Abyan Governorate Yemen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"AlKhalaf","sequence":"additional","affiliation":[{"name":"Imam Abdulrahman Bin Faisal University  Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sultan","family":"AlSalmi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, King Fahad University Hospital Imam Abdulrahman Bin Faisal University  Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2024.1805"},{"key":"e_1_2_12_3_1","volume-title":"StatPearls","author":"Master S. 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S.","year":"2015","journal-title":"Turkish Neurosurgery"},{"issue":"9","key":"e_1_2_12_14_1","first-page":"E308","article-title":"Aggressive Postoperative Lumbar Fibromatosis After the Placement of Instrumentation for Spondylolisthesis: Case Report","volume":"31","author":"G\u00fczey F. K.","year":"2006","journal-title":"Spine"},{"issue":"2","key":"e_1_2_12_15_1","first-page":"137","article-title":"Desmoid Tumor Formation Following Posterior Spinal Instrumentation for Vertebral Hemangioma: Case Report","volume":"4","author":"Puvanesarajah V.","year":"2013","journal-title":"Journal of Neurosurgery: Spine"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9124012"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2210140"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73181","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T05:34:34Z","timestamp":1787117674000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/ccr3.73181"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73181","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73181"}}