{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:50:38Z","timestamp":1761745838670,"version":"3.41.2"},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec><jats:title>Key clinical message<\/jats:title><jats:p>Delayed presentation of cerebrospinal fluid rhinorrhea is rare following head trauma. It is frequently complicated by meningitis if not addressed in time. This report highlights the importance of its timely management, the lack of which can lead to a fatal outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>A 33\u2010year\u2010old man presented with meningitis in septic shock. He had a history of severe traumatic brain injury 5\u2009years back following which he had a history of intermittent nasal discharge for the past 1\u2009year. On investigation, he was found to have <jats:italic>Streptococcus pneumoniae<\/jats:italic> meningitis, and CT scan of his head showed defects in the cribriform plate which established the diagnosis of meningoencephalitis secondary to cerebrospinal fluid rhinorrhea. The patient did not survive despite appropriate antibiotics.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.7320","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T11:03:01Z","timestamp":1683716581000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Delayed <scp>CSF<\/scp> rhinorrhea presenting as a lethal acute bacterial meningitis 5 years post trauma"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6218-9716","authenticated-orcid":false,"given":"Bipin","family":"Karki","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Maharajgunj Medical Campus Institute of Medicine  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Utsav","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Maharajgunj Medical Campus Institute of Medicine  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1355-944X","authenticated-orcid":false,"given":"Bishika","family":"Pun","sequence":"additional","affiliation":[{"name":"Department of Radiology Om Hospital and Research Center  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5890-0018","authenticated-orcid":false,"given":"Pramesh Sunder","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Maharajgunj Medical Campus Institute of Medicine  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005402"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-001-0059-7"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.08.067"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000008493"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino11.124"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.2500\/ar.2015.6.0132"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/ajns.AJNS_95_18"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1623"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T08:46:27Z","timestamp":1692434787000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/ccr3.7320"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7320","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"2023-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7320"}}