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In this report we discuss a case of a popliteal artery aneurysm caused by cystic medial necrosis that led to distal embolization. Right lower extremity excision of the popliteal artery aneurysm with placement of an interposition graft using reversed great saphenous vein was used in our case and can be used in other cases for treatment and prevention of further embolization.<\/jats:p>","DOI":"10.1002\/ccr3.73223","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:25:26Z","timestamp":1787732726000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cystic Medial Degeneration Leading to Popliteal Artery Aneurysm With Distal Embolization"],"prefix":"10.1002","volume":"14","author":[{"given":"Victor","family":"Cabrera\u2010Bou","sequence":"first","affiliation":[{"name":"UCF\/HCA Healthcare GME Consortium  Greater Orlando Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7641-8360","authenticated-orcid":false,"given":"Tuleagh","family":"Innes\u2010Gawn","sequence":"additional","affiliation":[{"name":"UCF\/HCA Healthcare GME Consortium  Greater Orlando Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Levitt","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Orlando Health  Orlando Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Calderin","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Osceola Regional Medical Center  Kissimmee Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"54","article-title":"Popliteal Artery Aneurysms. 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