{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:21:26Z","timestamp":1789154486553,"version":"build-2803163510"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T00:00:00Z","timestamp":1785628800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Cardiac sarcoidosis can be life\u2010threatening, and lack of response to immunosuppressive therapy remains a significant challenge in active disease. We present a case of refractory cardiac sarcoidosis despite third\u2010line immunosuppression (infliximab). Ongoing multimodality assessment is essential for managing refractory cardiac sarcoidosis.<\/jats:p>","DOI":"10.1002\/ccr3.73227","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T04:47:28Z","timestamp":1785732448000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Challenging Case of Advanced Cardiac Sarcoidosis Refractory to Infliximab Therapy"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9825-4102","authenticated-orcid":false,"given":"Manal","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Department of Cardiology Royal Brompton Hospital, Part of Guy's and St Thomas's NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2319-8876","authenticated-orcid":false,"given":"Mansimran Singh","family":"Dulay","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Brompton Hospital, Part of Guy's and St Thomas's NHS Foundation Trust  London UK"},{"name":"School of Cardiovascular Medicine and Science King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6852-5370","authenticated-orcid":false,"given":"Kshama","family":"Wechalekar","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute Imperial College London  London UK"},{"name":"Nuclear Medicine Department Royal Brompton Hospital, Part of Guy's and St Thomas's NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2723-0928","authenticated-orcid":false,"given":"Vasileios","family":"Kouranos","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Brompton Hospital, Part of Guy's and St Thomas's NHS Foundation Trust  London UK"},{"name":"National Heart and Lung Institute Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9418-2655","authenticated-orcid":false,"given":"Rakesh","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Brompton Hospital, Part of Guy's and St Thomas's NHS Foundation Trust  London UK"},{"name":"School of Cardiovascular Medicine and Science King's College London  London UK"},{"name":"National Heart and Lung Institute Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,2]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2024.102892"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2024.102577"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.14d02.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-19-0508"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae356"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2019.07.067"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.02.010"},{"issue":"2","key":"e_1_2_12_9_1","article-title":"The Role of Infliximab in Treating Refractory Cardiac Sarcoidosis. Case Series and Systematic Review of Literature","volume":"41","author":"Ahmed R.","year":"2024","journal-title":"Sarcoidosis, Vasculitis, and Diffuse Lung Diseases"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2021.07.008"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73227","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73227","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:21:08Z","timestamp":1788153668000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/ccr3.73227"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73227","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-03-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73227"}}