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We report a 75\u2010year\u2010old woman with recurrent ST\u2010elevation myocardial infarction and stent thrombosis after premature dual antiplatelet therapy interruption. Revascularization was successful, and eptifibatide bridging enabled safe surgery. This case highlights the risks of interruption and the role of bridging therapy.<\/jats:p>","DOI":"10.1002\/ccr3.73264","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:43:55Z","timestamp":1785386635000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Therapeutic Dilemma: Catastrophic\n                    <scp>ST<\/scp>\n                    \u2010Elevation Myocardial Infarction Following Antiplatelet Therapy Interruption in a Patient With\n                    <scp>JAK2<\/scp>\n                    \u2010Positive Polycythemia Vera"],"prefix":"10.1002","volume":"14","author":[{"given":"Behrouz","family":"zarei","sequence":"first","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Hormozgan University of Medical Sciences  Bandar Abbas Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9894-1015","authenticated-orcid":false,"given":"Amirhossein","family":"Rezaei Latifi","sequence":"additional","affiliation":[{"name":"Student Research Committee Hormozgan University of Medical Sciences  Bandar Abbas Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1100-6161","authenticated-orcid":false,"given":"Mohammad","family":"Salari","sequence":"additional","affiliation":[{"name":"Student Research Committee Hormozgan University of Medical Sciences  Bandar Abbas Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1369701"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v15.i11.571"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-949664"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12071746"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-03-460154"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-019-03625-x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15648"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jha2.70088"},{"key":"e_1_2_12_10_1","first-page":"CD006503","article-title":"Antiplatelet Drugs for Polycythaemia Vera and Essential Thrombocythaemia","volume":"4","author":"Squizzato A.","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.636675"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S429995"},{"key":"e_1_2_12_13_1","article-title":"The CARE Guidelines: Consensus\u2010Based Clinical Case Reporting Guideline Development","volume":"2023","author":"Gagnier J. 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