{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:55:11Z","timestamp":1791273311495,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Risk stratification in congenital long QT syndrome (LQTS) continues to rely heavily on genotype and QTc duration, despite their limited ability to identify individuals at highest arrhythmic risk. The electromechanical window (EMW) is a validated marker of malignant arrhythmia susceptibility, yet its presence within routine echocardiographic imaging has not been recognized. We report a 19\u2010year\u2010old woman with\n                    <jats:italic>KCNH2<\/jats:italic>\n                    \u2010related LQTS who experienced recurrent syncope triggered by abrupt auditory stimuli, with ambulatory monitoring revealing self\u2010terminating torsades de pointes up to 273 beats\/min. Although cardiac magnetic resonance and standard echocardiography showed normal structure, retrospective analysis of archived routine cine loops revealed marked EMW negativity (mean \u221297.5\u2009ms), measurable directly from standard imaging without specialized acquisition. Retrospective analysis demonstrated that marked EMW negativity was measurable from routine echocardiographic images acquired before the diagnosis was established. This case suggests that EMW negativity may be silently present in many previously imaged LQTS patients and recoverable retrospectively from existing echocardiographic datasets.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.73336","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:46:09Z","timestamp":1788410769000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hidden in Plain Sight: Electromechanical Window Negativity in Congenital Long\n                    <scp>QT<\/scp>\n                    Syndrome"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6604-9568","authenticated-orcid":false,"given":"Toby","family":"Paterson","sequence":"first","affiliation":[{"name":"Department of Natural Sciences Middlesex University  London UK"},{"name":"Department of Cardiology North West Anglia Hospital  Peterborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7881-1860","authenticated-orcid":false,"given":"Roy","family":"Sanders","sequence":"additional","affiliation":[{"name":"Department of Cardiology North West Anglia Hospital  Peterborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9612-1947","authenticated-orcid":false,"given":"Vivetha","family":"Pooranachandran","sequence":"additional","affiliation":[{"name":"Department of Natural Sciences Middlesex University  London UK"},{"name":"Department of Cardiology Sheffield Teaching Hospital  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"e_1_2_17_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac135"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2021.01.006"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn466"},{"key":"e_1_2_17_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2024.06.012"},{"key":"e_1_2_17_6_1","first-page":"3997","article-title":"2022 ESC Guidelines for the Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death","volume":"43","author":"Zeppenfeld K.","year":"2022","journal-title":"European Society of Cardiology"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu370"},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.985"},{"issue":"12","key":"e_1_2_17_9_1","first-page":"1427","article-title":"Application of Electromechanical Window Negativity as an Arrhythmia Risk Correlate in Acquired Long QT Syndrome","volume":"3","author":"Munshi F.","year":"2021","journal-title":"Case Reports"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2023.38.e186"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s44156-022-00003-8"},{"issue":"13","key":"e_1_2_17_12_1","first-page":"272","article-title":"2017 AHA\/ACC\/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death","volume":"138","author":"Al\u2010Khatib S. M.","year":"2017","journal-title":"Circulation"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73336","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73336","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73336","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:38:26Z","timestamp":1791272306000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/ccr3.73336"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73336","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2026-05-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73336"}}