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Diagnostic workup confirmed systemic lupus erythematosus with triple\u2010positive antiphospholipid antibodies. Imaging revealed bilateral middle cerebral artery thrombosis, meeting criteria for catastrophic antiphospholipid syndrome triggered by active tuberculosis. Prompt initiation of corticosteroids, anticoagulation, and immunosuppression was critical to achieving clinical stabilization.<\/jats:p>","DOI":"10.1002\/ccr3.73362","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T04:44:22Z","timestamp":1787201062000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rare Pediatric Male Presentation of Systemic Lupus Erythematosus With Catastrophic Antiphospholipid Syndrome Following Pulmonary Tuberculosis: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6972-4440","authenticated-orcid":false,"given":"Asma","family":"Qureshi","sequence":"first","affiliation":[{"name":"Department of Medicine Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8311-2064","authenticated-orcid":false,"given":"Mahaveer","family":"Maheshwari","sequence":"additional","affiliation":[{"name":"Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3028-1757","authenticated-orcid":false,"given":"Aasiya Shahbaz","family":"Sakarwala","sequence":"additional","affiliation":[{"name":"Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7699-5321","authenticated-orcid":false,"given":"Umaya","family":"Memon","sequence":"additional","affiliation":[{"name":"Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5588-9892","authenticated-orcid":false,"given":"Vishan","family":"Das","sequence":"additional","affiliation":[{"name":"Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mumtaz Ali","family":"Lakho","sequence":"additional","affiliation":[{"name":"Department of Medicine Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4960-9237","authenticated-orcid":false,"given":"Sandesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Ghafoor","sequence":"additional","affiliation":[{"name":"Liaquat University of Medical and Health Sciences  Jamshoro Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4712-4574","authenticated-orcid":false,"given":"Siddhant Kumar","family":"Yadav","sequence":"additional","affiliation":[{"name":"Patan Academy of Health Sciences  Lalitpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010025\u201002168\u20100"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14030733"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25010668"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926\u2010025\u201001207\u20107"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.66555"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X221085099"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100043\u20101764472"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.69730"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.30330"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X251379588"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu394oa"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfae302"},{"issue":"1","key":"e_1_2_15_14_1","first-page":"81","article-title":"Pulmonary Tuberculosis\u2010Induced Coagulation Disorder\u2014A Case Series","volume":"6","author":"Salve P. 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