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In this case, diabetes mellitus was diagnosed several years before psychiatric symptoms, which were then followed by neurological decline, which significantly delayed diagnosis. This case highlights the importance of considering metabolic and neurodegenerative causes in atypical psychiatric presentations and expands the genetic spectrum with a novel CP gene mutation.<\/jats:p>","DOI":"10.1002\/ccr3.73366","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T04:20:18Z","timestamp":1787372418000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Aceruloplasminemia Presenting With Prominent Psychiatric Symptoms and Neurodegeneration: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0410-9037","authenticated-orcid":false,"given":"Ali","family":"Almarzooqi","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Dubai Health Rashid Hospital  Dubai UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7776-1644","authenticated-orcid":false,"given":"Abdulrahman","family":"Almarzooqi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Dubai Health Rashid Hospital  Dubai UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5227-5772","authenticated-orcid":false,"given":"Khalifa","family":"Juma","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Dubai Health Rashid Hospital  Dubai UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0832-4849","authenticated-orcid":false,"given":"Hamda","family":"Kamalboor","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Dubai Health Rashid Hospital  Dubai UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1789.2003.00521.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00325"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/138945012802002320"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2018170079"},{"key":"e_1_2_10_6_1","doi-asserted-by":"crossref","unstructured":"H.MiyajimaandY.Hosoi \u201cAceruloplasminemia \u201d (2018).","DOI":"10.5772\/intechopen.71831"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2018.02.036"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12149"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12712"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/nsn.nsn_23_24"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.12.015"},{"issue":"3","key":"e_1_2_10_12_1","first-page":"657","article-title":"MR Imaging of Cerebral Cortical Involvement in Aceruloplasminemia","volume":"26","author":"Grisoli M.","year":"2005","journal-title":"American Journal of Neuroradiology"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.04.039"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2007.01.001"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73366","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:23:03Z","timestamp":1788153783000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/ccr3.73366"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73366","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2025-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73366"}}