{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:54:51Z","timestamp":1791273291246,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder characterized by bone fragility and Type I collagen defects. Although dentinogenesis imperfecta (DI) is a classic manifestation, patients with OI may experience significant dental deterioration even in its absence due to inherent dentinal weakness. This report describes the multidisciplinary full\u2010mouth rehabilitation of a 18\u2010year\u2010old male with OI and a complex medical history including autoimmune hepatitis and seizure disorder. The patient presented with extensive caries, failure of previous restorations, multiple impacted teeth, and radiographic evidence of preeruptive intracoronal resorption (PEIR) as well as open apices in permanent second molars. Severe microstomia, joint laxity, high risk of iatrogenic jaw fracture, and limited cooperation necessitated treatment under general anesthesia. Management included vital pulp therapy to promote apexogenesis in immature teeth, stainless steel crowns for posterior rehabilitation, and composite restorations using universal adhesive systems containing 10\u2010MDP. A conservative, non\u2010extraction strategy was adopted to minimize mandibular fracture risk. This case highlights that dental pathology in OI may originate within bone prior to eruption and emphasizes the importance of biologically driven and fracture\u2010conscious treatment planning in medically complex patients.<\/jats:p>","DOI":"10.1002\/ccr3.73383","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T07:12:34Z","timestamp":1787555554000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multidisciplinary Oral Rehabilitation in Osteogenesis Imperfecta: 18\u2010Year\u2010Old Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0996-1193","authenticated-orcid":false,"given":"Pegah Mosannen","family":"Mozafari","sequence":"first","affiliation":[{"name":"Shahab Dental Clinic (Oral Medicine and Special Care Dentistry)  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1745-9227","authenticated-orcid":false,"given":"Mahsa Talafi","family":"Noghani","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5728-6973","authenticated-orcid":false,"given":"Iman","family":"Kashani","sequence":"additional","affiliation":[{"name":"Pediatric Anesthesia, Department of Pediatrics, Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4422-229X","authenticated-orcid":false,"given":"Reza","family":"Beyragh","sequence":"additional","affiliation":[{"name":"Private Dental Practice  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sdentj.2013.10.004"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2023-0040"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-024-01293-2"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2007.tb01757.x"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00924"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.13112\/pc.522"},{"key":"e_1_2_15_8_1","unstructured":"S. N. M.SockalingamandA. S.Irfani Comprehensive Dental Rehabilitation of an Osteogenesis Imperfecta Child With Dentinogenesis Imperfecta Type."},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2020.03.003"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-019-00424-w"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-018-0639-7"},{"issue":"1","key":"e_1_2_15_12_1","article-title":"Regenerative Therapy in Comprehensive Oral Rehabilitation for Pediatric Osteogenesis Imperfecta: A Case Report","volume":"17","author":"Goswami M.","year":"2025","journal-title":"Cureus"},{"issue":"2","key":"e_1_2_15_13_1","first-page":"133","article-title":"Dental Management of a Child With Dentinogenesis Imperfecta: A Case Report","volume":"13","author":"Akhlaghi N.","year":"2016","journal-title":"Journal of Dentistry"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-246554"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.30.1.t53201466660612r"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1590\/1981-863720200005020190074"},{"issue":"1","key":"e_1_2_15_17_1","first-page":"10","article-title":"Oral Rehabilitation of a Pediatric Patient With Osteogenesis Imperfecta Type VII: A Case Report","volume":"3","author":"Tekin B.","year":"2024","journal-title":"Journal of Clinical Trials and Experimental Investigations"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103-644020256485"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/jdmimsu.jdmimsu_46_19"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73383","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73383","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73383","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:39:21Z","timestamp":1791272361000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,24]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/ccr3.73383"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73383","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,24]]},"assertion":[{"value":"2026-02-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73383"}}