{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:55:01Z","timestamp":1791273301059,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We report a 36\u2010year\u2010old woman who presented with acute visual hallucinations, delusions, and dizziness 2\u2009months after uncomplicated kidney transplantation. Brain magnetic resonance imaging (MRI) revealed T2\/FLAIR hyperintensities in the dorsal pons and bilateral temporal cortices, atypical yet consistent with PRES. Tacrolimus\u2010induced PRES was diagnosed in the absence of severe hypertension or other precipitants. Tacrolimus was discontinued and replaced with cyclosporine, with complete clinical resolution and normalization of MRI findings within 8\u2009weeks. This case underscores the importance of prompt clinical suspicion and discontinuation of tacrolimus in transplant recipients with neuropsychiatric symptoms and supportive neuroimaging, even with atypical lesion distribution. Close therapeutic drug monitoring and rapid immunosuppressant adjustment can facilitate full recovery and prevent permanent sequelae.<\/jats:p>","DOI":"10.1002\/ccr3.73386","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T04:36:59Z","timestamp":1787546219000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tacrolimus\u2010Induced Atypical Posterior Reversible Encephalopathy Syndrome (\n                    <scp>PRES<\/scp>\n                    ) in a Kidney Transplant Recipient: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Roya","family":"Sadeghnia","sequence":"first","affiliation":[{"name":"Kidney Transplantation Complications Research Center Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5647-8205","authenticated-orcid":false,"given":"Sayed Mortaza","family":"Fayez","sequence":"additional","affiliation":[{"name":"Student Research Committee, Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0132-4491","authenticated-orcid":false,"given":"Sara","family":"Samadi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,23]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8377-8"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2012.00152"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00111-8"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003173"},{"issue":"3","key":"e_1_2_13_6_1","article-title":"Posterior Reversible Encephalopathy Syndrome With Hemorrhagic Transformation in the Postoperative Period of a Kidney Transplant","volume":"16","author":"Dehesa\u2010Lopez E.","year":"2024","journal-title":"Cureus"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000207622"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602223340803"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2009.0590"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22408"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2024"},{"issue":"10","key":"e_1_2_13_12_1","article-title":"An Atypical Presentation of Posterior Reversible Encephalopathy Syndrome (PRES): Sticking to the Basics","volume":"16","author":"Ebrahim Essa N. 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