{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:54:49Z","timestamp":1791273289310,"version":"4.1.0"},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Bartter syndrome is a rare autosomal recessive renal tubulopathy, which classically presents with hypokalemic metabolic alkalosis, hyperreninemia, and hyperaldosteronism. We report an atypical presentation in a 16\u2010year\u2010old male who was diagnosed following an initial manifestation of acute pancreatitis. Key biochemical findings included profound hypokalemia (1.4\u2009mEq\/L), metabolic alkalosis, hyperreninemia (218.5 uIU\/mL), and hypercalciuria, yet with a normal serum aldosterone level, which is a notable deviation from the classic biochemical profile. The acute pancreatitis was attributed to severe hypokalemia\u2010induced pancreatic ductal dysfunction. This case underscores that a normal aldosterone level does not exclude Bartter syndrome and emphasizes the importance of considering this possibility in patients with hypokalemic alkalosis and renal salt\u2010wasting. Furthermore, it highlights severe hypokalemia as a potential, life\u2010threatening precipitant of acute pancreatitis, warranting prompt investigation in affected patients presenting with acute abdominal pain.<\/jats:p>","DOI":"10.1002\/ccr3.73418","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T06:21:40Z","timestamp":1788330100000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bartter Syndrome With Normal Aldosterone Level and Acute Pancreatitis: An Unusual Presentation"],"prefix":"10.1002","volume":"14","author":[{"given":"Noor","family":"Ayaz","sequence":"first","affiliation":[{"name":"Department of Medicine Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Medical College  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqar","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhan","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikram Ullah","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Naim","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awais","family":"Naeem","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Teaching Hospital  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8861-0367","authenticated-orcid":false,"given":"Fatima","family":"Sajjad","sequence":"additional","affiliation":[{"name":"Department of Medicine Khyber Medical College  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8208-0689","authenticated-orcid":false,"given":"Kamil Ahmad","family":"Kamil","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Nasrat Bashir Curative Hospital  Kandahar Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"issue":"2","key":"e_1_2_12_2_1","first-page":"366","article-title":"Bartter Syndrome With Normal Aldosterone Level: An Unusual Presentation","volume":"25","author":"Huque S. S.","year":"2016","journal-title":"Mymensingh Medical Journal"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.15171\/jnp.2017.59"},{"key":"e_1_2_12_4_1","volume-title":"StatPearls [Internet]","author":"Bokhari S. R. A."},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-011-1871-4"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200012000-00009"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000065373"},{"key":"e_1_2_12_8_1","first-page":"341","volume-title":"The Pancreas: Biology, Pathobiology, and Disease","author":"Lee M. 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