{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:55:14Z","timestamp":1791273314568,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Papillon\u2013Lef\u00e8vre syndrome is a rare autosomal recessive disorder characterized by palmoplantar keratoderma and aggressive periodontitis. We report an 11\u2010year\u2010old Nepalese girl presenting with severe periodontal destruction and characteristic cutaneous manifestations. Clinical and radiographic findings established the diagnosis. Early multidisciplinary management is essential to preserve function and improve quality of life.<\/jats:p>","DOI":"10.1002\/ccr3.73435","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:36:30Z","timestamp":1788154590000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Aggressive Periodontitis and Palmoplantar Keratoderma: Papillon\u2013Lef\u00e8vre Syndrome in an 11\u2010Year\u2010Old Nepalese Girl"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9359-3113","authenticated-orcid":false,"given":"Jenisha","family":"Bhattarai","sequence":"first","affiliation":[{"name":"Nepal Medical College and Teaching Hospital  Kathmandu Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8382-6761","authenticated-orcid":false,"given":"Sanish","family":"Pokhrel","sequence":"additional","affiliation":[{"name":"Devdaha Nagar Hospital  Rupandehi Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9973-2898","authenticated-orcid":false,"given":"Yogendra","family":"Poudel","sequence":"additional","affiliation":[{"name":"Nepal Medical College and Teaching Hospital  Kathmandu Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5131-5247","authenticated-orcid":false,"given":"Ujjwal","family":"Rimal","sequence":"additional","affiliation":[{"name":"Kist Medical College and Teaching Hospital  Kathmandu Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.43335"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972\u2010124X.99273"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.20517\/2573\u20100002.2018.22"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00278288"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000245341"},{"issue":"12","key":"e_1_2_12_7_1","first-page":"1197","article-title":"Papillon\u2010Lef\u00e8vre Syndrome","volume":"40","author":"Mahajan V. 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