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We report a case of obstructive jaundice caused by a periportal tuberculous mass confirmed by fine\u2010needle aspiration and GeneXpert. Treatment was complicated by anti\u2010tuberculous drug\u2010induced liver injury. Tuberculosis should be considered in the differential diagnosis in endemic settings.<\/jats:p>","DOI":"10.1002\/ccr3.73443","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T04:20:09Z","timestamp":1788754809000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Obstructive Jaundice due to a Periportal Tuberculous Mass Complicated by Anti\u2010Tuberculous Drug\u2010Induced Liver Injury: A Case Report From a Low\u2010Resource Setting"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5397-9326","authenticated-orcid":false,"given":"Girma Deshimo","family":"Lema","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Debre Berhan University  Debre Berhan Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yemisrach","family":"Chanie","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathewos Tesfaye","family":"Yanore","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0892-4964","authenticated-orcid":false,"given":"Segenet Bizuneh","family":"Mengistu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Gondar  Gondar Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanuel Berhanu","family":"Kotisso","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawit","family":"Zena","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Arsi University  Asella Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saymen Tsegaye","family":"Gebreeyesus","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Aksum University  Aksum Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadesse Mulusew","family":"Gared","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebyu Samuel","family":"Chekol","sequence":"additional","affiliation":[{"name":"Department of Radiology St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebrahim Umer","family":"Muhammed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Adama Hospital Medical College  Adama Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,6]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2022.43.146.35557"},{"key":"e_1_2_14_3_1","volume-title":"Global Tuberculosis Report 2025","author":"World Health Organization","year":"2025"},{"key":"e_1_2_14_4_1","article-title":"Extrapulmonary Tuberculosis: Update on the Epidemiology, Risk Factors and Prevention Strategies","volume":"1","author":"Ben Ayed H.","year":"2018","journal-title":"International Journal of Tropical Disease & Health"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijmy.ijmy_195_21"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2013.39799"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000066097"},{"issue":"4","key":"e_1_2_14_8_1","article-title":"Obstructive Jaundice due to Periportal Tuberculous Lymphadenopathy in a Patient With Multidrug\u2010Resistant (MDR) Tuberculosis: A Case Report","volume":"18","author":"Mali A.","year":"2026","journal-title":"Cureus"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-024-02070-2"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.12187"},{"key":"e_1_2_14_11_1","volume-title":"Treatment of Tuberculosis: Guidelines","author":"World Health Organization and S.T. 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