{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:40:35Z","timestamp":1792269635766,"version":"4.4.0"},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We report a case of carbamazepine\u2010induced Stevens\u2010Johnson syndrome\/toxic epidermal necrolysis (SJS\/TEN) overlap in an 11\u2010year\u2010old Ugandan boy who presented with fever, facial swelling, ocular redness with photophobia, painful oral ulceration, and widespread epidermal detachment involving more than 10% of the body surface area. Symptoms developed 10\u2009days after initiation of carbamazepine for newly diagnosed epilepsy. Examination revealed extensive mucocutaneous involvement characterized by bilateral eyelid edema, conjunctival inflammation, perioral hemorrhagic crusting, erosive oral ulcers, and a positive Nikolsky sign. A clinical diagnosis of carbamazepine\u2010induced SJS\/TEN overlap was established based on the temporal relationship to drug exposure and characteristic clinical findings. Immediate withdrawal of carbamazepine and multidisciplinary supportive care resulted in marked clinical improvement. This case highlights the importance of early recognition, prompt withdrawal of the offending drug, and multidisciplinary supportive care in improving outcomes for pediatric SJS\/TEN, particularly in resource\u2010limited settings.<\/jats:p>","DOI":"10.1002\/ccr3.73474","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T06:55:06Z","timestamp":1788504906000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Carbamazepine\u2010Induced Stevens\u2010Johnson Syndrome\/Toxic Epidermal Necrolysis Overlap With Severe Ocular and Oral Involvement: A Pediatric Case Report From Uganda"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7328-3195","authenticated-orcid":false,"given":"Abdisalam Ahmed","family":"Sandeyl","sequence":"first","affiliation":[{"name":"Internal Medicine Department Kampala International University Western Campus  Bushenyi Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdisamad Guled","family":"Hersi","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Kampala International University Western Campus  Bushenyi Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakarie Abdullahi","family":"Hussein","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Kampala International University Western Campus  Bushenyi Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2594-6728","authenticated-orcid":false,"given":"Mohamed Farah","family":"Ismail","sequence":"additional","affiliation":[{"name":"Opthalmology Department Kampala International University Western Campus  Bushenyi Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullahi Ali","family":"Bulle","sequence":"additional","affiliation":[{"name":"Surgery Department Kampala International University Western Campus  Bushenyi Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoun","family":"Nasr","sequence":"additional","affiliation":[{"name":"Dermatology Department Kampala International University Western Campus  Bushenyi Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57090895"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14530"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010024\u201000889\u20106"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40801\u2010017\u20100105\u2010x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jped.2025.101455"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/6128688"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.00527"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40123\u2010023\u201000725\u2010w"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/IJO.IJO_1119_25"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523\u20101747.2000.00061.x"}],"container-title":["Clinical 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