{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:01:19Z","timestamp":1790226079134,"version":"4.1.0"},"reference-count":9,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Congenital uterine anomalies are an important and potentially treatable contributor to recurrent pregnancy loss (RPL). The septate uterus is the commonest M\u00fcllerian anomaly linked to first\u2010trimester loss, and its differentiation from the benign arcuate uterus is essential for management, yet imaging modalities may disagree. We report the case of a 23\u2010year\u2010old woman (G2P0A2) who presented with oligomenorrhea and two consecutive spontaneous first\u2010trimester miscarriages. Initial transvaginal ultrasound suggested a septate uterus, whereas pelvic magnetic resonance imaging indicated an arcuate uterus, resulting in diagnostic confusion. Diagnostic hysteroscopy revealed a thick, fibrous partial septum, and simultaneous hysteroscopic septoplasty was performed. A complete RPL evaluation was not possible: antiphospholipid antibody testing, parental karyotyping, and genetic analysis of products of conception were unavailable, so alternative etiologies could not be excluded and the septum cannot be established as the sole cause of the miscarriages. Comprehensive endocrine assessment was likewise unavailable, leaving ovulatory dysfunction incompletely characterized; a lean polycystic ovary syndrome phenotype could not be excluded. Following septoplasty and subsequent ovulation induction with letrozole, she conceived and delivered a healthy male infant at term by cesarean section. Because conception occurred only after letrozole, the relative contributions of these two sequential interventions cannot be distinguished. Second\u2010look hysteroscopy was not performed, so restoration of a normal cavity was never objectively confirmed and residual septum or intrauterine adhesions could not be excluded before conception. This case demonstrates the diagnostic value of hysteroscopy in resolving discordant imaging while emphasizing that the outcome must not be attributed to septoplasty alone.<\/jats:p>","DOI":"10.1002\/ccr3.73515","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:20:17Z","timestamp":1790223617000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Discordance in Recurrent Pregnancy Loss: Hysteroscopy Resolves Ultrasound\u2013\n                    <scp>MRI<\/scp>\n                    Disagreement in Septate Uterus, but Concurrent Ovulation Induction Precludes Causal Attribution of the Reproductive Outcome"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3772-695X","authenticated-orcid":false,"given":"Iftekhar Ahmed","family":"Sakib","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Shaheed Suhrawardy Medical College  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesa","family":"Perveen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shaheed Suhrawardy Medical College  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishad","family":"Tasnim","sequence":"additional","affiliation":[{"name":"University of Dhaka  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"issue":"6","key":"e_1_2_13_2_1","first-page":"1151","article-title":"Evaluation and Treatment of Recurrent Pregnancy Loss: A Committee Opinion","volume":"114","author":"Practice Committee of the American Society for Reproductive Medicine","year":"2020","journal-title":"Fertility and Sterility"},{"issue":"8","key":"e_1_2_13_3_1","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1093\/humrep\/det098","article-title":"The ESHRE\/ESGE Consensus on the Classification of Female Genital Tract Congenital Anomalies","volume":"28","author":"Grimbizis G. F.","year":"2013","journal-title":"Human Reproduction"},{"issue":"6","key":"e_1_2_13_4_1","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/uog.127","article-title":"Reproducibility of Three\u2010Dimensional Ultrasound Diagnosis of Congenital Uterine Anomalies","volume":"21","author":"Salim R.","year":"2003","journal-title":"Ultrasound in Obstetrics & Gynecology"},{"issue":"1","key":"e_1_2_13_5_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jmig.2012.09.010","article-title":"Hysteroscopic Metroplasty for the Septate Uterus: Review and Meta\u2010Analysis","volume":"20","author":"Valle R. F.","year":"2013","journal-title":"Journal of Minimally Invasive Gynecology"},{"issue":"5","key":"e_1_2_13_6_1","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/uog.7551","article-title":"Three\u2010Dimensional Ultrasound in the Diagnosis of M\u00fcllerian Duct Anomalies and Concordance With Magnetic Resonance Imaging","volume":"35","author":"Bermejo C.","year":"2010","journal-title":"Ultrasound in Obstetrics & Gynecology"},{"issue":"1","key":"e_1_2_13_7_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0015-0282(99)00480-X","article-title":"The Septate Uterus: A Review of Management and Reproductive Outcome","volume":"73","author":"Homer H. A.","year":"2000","journal-title":"Fertility and Sterility"},{"issue":"6","key":"e_1_2_13_8_1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.rbmo.2014.09.006","article-title":"Clinical Implications of Congenital Uterine Anomalies: A Meta\u2010Analysis of Comparative Studies","volume":"29","author":"Venetis C. A.","year":"2014","journal-title":"Reproductive Biomedicine Online"},{"issue":"3","key":"e_1_2_13_9_1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.7863\/jum.2008.27.3.413","article-title":"The Role of Three\u2010Dimensional Ultrasonography and Magnetic Resonance Imaging in the Diagnosis of M\u00fcllerian Duct Anomalies","volume":"27","author":"Deutch T. D.","year":"2008","journal-title":"Journal of Ultrasound in Medicine"},{"key":"e_1_2_13_10_1","first-page":"124","article-title":"Septum Resection Versus Expectant Management in Women With a Septate Uterus: An International Multicentre Open\u2010Label Randomized Controlled Trial (TRUST)","volume":"385","author":"Rikken J. F. W.","year":"2021","journal-title":"New England Journal of Medicine"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73515","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73515","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73515","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:20:19Z","timestamp":1790223619000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/ccr3.73515"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73515","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]},"assertion":[{"value":"2025-12-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73515"}}