{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:01:11Z","timestamp":1790604071951,"version":"4.1.0"},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Motor neurone disease (MND) presents significant perioperative challenges due to progressive respiratory muscle weakness, bulbar dysfunction, autonomic instability, and altered sensitivity to anesthetic agents. Emergency surgery further limits opportunities for optimisation and advance planning. We report the perioperative and anesthetic management of a patient with advanced MND undergoing emergency laparotomy for small bowel obstruction. A total intravenous anesthetic with cautious use of neuromuscular blockade was employed, and the patient was successfully extubated postoperatively. Despite an initially uncomplicated postoperative course, the patient subsequently developed progressive respiratory failure in the context of ongoing intra\u2010abdominal pathology. Following multidisciplinary discussion and shared decision\u2010making, care was transitioned to a comfort\u2010focused approach. This case highlights the limitations of perioperative intervention in advanced MND and emphasizes the importance of goal\u2010concordant care in emergency surgical settings.<\/jats:p>","DOI":"10.1002\/ccr3.73635","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:21:12Z","timestamp":1790601672000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anesthetic Management and Perioperative Outcome of Emergency Laparotomy in a Patient With Advanced Motor Neurone Disease: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2745-3808","authenticated-orcid":false,"given":"Sherif","family":"Elmahgoub","sequence":"first","affiliation":[{"name":"Galway University Hospital  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdou","family":"Elshawa","sequence":"additional","affiliation":[{"name":"Galway University Hospital  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Flannery","sequence":"additional","affiliation":[{"name":"Galway University Hospital  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"issue":"5","key":"e_1_2_14_2_1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1177\/0310057X211065042","article-title":"Perioperative Management of Patients With Amyotrophic Lateral Sclerosis: A Narrative Review","volume":"50","author":"Paul D.","year":"2022","journal-title":"Anaesthesia and Intensive Care"},{"issue":"3","key":"e_1_2_14_3_1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/mus.23817","article-title":"Neuromuscular Disease and Anesthesia","volume":"48","author":"Romero A.","year":"2013","journal-title":"Muscle & Nerve"},{"issue":"4","key":"e_1_2_14_4_1","first-page":"419","article-title":"Recommendations for Anesthesia and Perioperative Management of Patients With Neuromuscular Disorders","volume":"79","author":"Racca F.","year":"2013","journal-title":"Minerva Anestesiologica"},{"issue":"3","key":"e_1_2_14_5_1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/ACO.0000000000000466","article-title":"Anesthetic Considerations for Neuromuscular Diseases","volume":"30","author":"Katz J. 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R.","year":"2022","journal-title":"European Journal of Neurology"},{"key":"e_1_2_14_8_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2024.123049","article-title":"The Periprocedural Respiratory Safety of Propofol Sedation in Patients With a Motor Neuron Disease Undergoing Percutaneous Endoscopic Gastrostomy Insertion","volume":"461","author":"Van Neerven G. J. L.","year":"2024","journal-title":"Journal of the Neurological Sciences"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/ebm.2024.10401"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73635","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.73635","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.73635","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:21:14Z","timestamp":1790601674000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.73635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,28]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/ccr3.73635"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.73635","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,28]]},"assertion":[{"value":"2026-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73635"}}