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Although pregnancy raises factor levels, her response was insufficient. Desmopressin successfully controlled mucosal hemorrhage, avoiding antifibrinolytics due to obstructive risk. Management requires multidisciplinary surveillance to tailor peripartum hemostatic interventions.<\/jats:p>","DOI":"10.1002\/ccr3.73728","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T04:56:39Z","timestamp":1791780999000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8802-3095","authenticated-orcid":false,"given":"Jose Luis","family":"Rojas\u2010Oviedo","sequence":"first","affiliation":[{"name":"Universidad Nacional de Colombia  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1672-0620","authenticated-orcid":false,"given":"Mar\u00eda Fernanda Leal","family":"Walteros","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5087-7885","authenticated-orcid":false,"given":"Dauris Lineth Mej\u00eda","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia  Bogot\u00e1 Colombia"},{"name":"Subred Integrada de Servicios de Salud Norte  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Eliecer Castellanos","family":"Corredor","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Sur  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danna Geraldinne Amaya","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Gynecology Department Subred Integrada de Servicios de Salud Sur  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Sof\u00eda Lancheros","family":"Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Universitaria San Mart\u00edn  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,11]]},"reference":[{"issue":"4","key":"e_1_2_13_2_1","first-page":"254","article-title":"Current Approaches to Pregnancy and Childbirth in Women With von Willebrand Disease","volume":"16","author":"Johnsen J. 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