{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:40:47Z","timestamp":1792734047433,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Hematologic malignancies involving the ovaries are rare and may mimic ovarian carcinoma. We report a 20\u2010year\u2010old woman who presented with generalized body pain, bilateral ovarian masses, and abdominal adenopathy, initially suspected to have ovarian carcinoma. Despite normal blood counts, a retroperitoneal lymph node biopsy and subsequent bone marrow biopsy confirmed B\u2010lymphoblastic leukemia. Molecular analysis identified multiple pathogenic alterations, including\n                    <jats:italic>CREBBP<\/jats:italic>\n                    ,\n                    <jats:italic>KMT2D<\/jats:italic>\n                    , and\n                    <jats:italic>KRAS<\/jats:italic>\n                    mutations,\n                    <jats:italic>CDKN2A<\/jats:italic>\n                    copy number loss, and\n                    <jats:italic>FLT3<\/jats:italic>\n                    overexpression. The patient developed tumor lysis syndrome and was transferred to a tertiary center, after which she was lost to follow\u2010up. While long\u2010term treatment response could not be evaluated, this case underscores the clinical necessity of including B\u2010lymphoblastic leukemia\/lymphoma in the differential diagnosis of bilateral ovarian masses in young women, even with normal peripheral blood counts. Early tissue diagnosis through minimally invasive biopsy is essential to avoid unnecessary surgery and to initiate appropriate systemic therapy.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.73736","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:45:26Z","timestamp":1792226726000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["B\u2010Lymphoblastic Leukemia Presenting as Bilateral Ovarian Masses in a 20\u2010Year\u2010Old Woman"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1877-0316","authenticated-orcid":false,"given":"Jennifer","family":"Cai","sequence":"first","affiliation":[{"name":"University of California Irvine  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sin","sequence":"additional","affiliation":[{"name":"Department of Radiology Harbor\u2010UCLA Medical Center  Torrance California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Varda","sequence":"additional","affiliation":[{"name":"Division of Hematology and Medical Oncology, Department of Medicine Harbor\u2010UCLA Medical Center  Torrance California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Lewis","sequence":"additional","affiliation":[{"name":"Division of Hematology and Medical Oncology, Department of Medicine Harbor\u2010UCLA Medical Center  Torrance California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Yeh","sequence":"additional","affiliation":[{"name":"Division of Hematology and Medical Oncology, Department of Medicine Harbor\u2010UCLA Medical Center  Torrance California USA"},{"name":"David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.74.2.149"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.5114\/pm.2023.128661"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gore.2016.10.001"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.000000000000020139417"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2022.03.026"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1309\/Q5GV\u20103K00\u2010WAC6\u2010BBUB"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347\u2010200404000\u201000017"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0b013e31815ea7e3"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032\u2010010\u20109578\u20100"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447\u20100756.2012.01984.x"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2016.11.012"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijmpo.ijmpo_144_16"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.199885"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.29299"},{"key":"e_1_2_12_16_1","first-page":"493","article-title":"Ovarian Lymphoma. 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