{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T15:56:09Z","timestamp":1764172569828,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human herpesvirus type 8 (HHV\u20108) unrelated primary effusion lymphoma (PEL) like lymphoma (PEL\u2010LL) is an exceedingly rare non\u2010Hodgkin lymphoma with no characteristic symptoms and consensus on the optimal treatment. This case report presents a 55\u2010year\u2010old man with prior HBV\u2010related Child\u2010Pugh B liver cirrhosis and developing activity\u2010related dyspnea. A moderate amount of pleural effusion was identified without tumor masses, and cytological studies confirmed a diagnosis of PEL\u2010LL. The patient received rituximab and lenalidomide, albeit with HBV infection, and is currently on maintenance therapy with resolving symptoms but without HBV reactivation. Hence, the R2 protocol (rituximab and lenalidomide) might be clinically effective and safe for PEL\u2010LL patients with HBV infection and Child\u2010Pugh B liver cirrhosis.<\/jats:p>","DOI":"10.1002\/ccr3.7411","type":"journal-article","created":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T06:43:42Z","timestamp":1685169822000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>HHV8<\/scp>\u2010unrelated primary effusion lymphoma in a patient with <scp>HBV<\/scp>\u2010related liver cirrhosis: A case successfully treated with rituximab and lenalidomide"],"prefix":"10.1002","volume":"11","author":[{"given":"Peng\u2010Jun","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Hematology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) South Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) South Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Juan","family":"Wei","sequence":"additional","affiliation":[{"name":"Department Lymphoma, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) South Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020002293"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpccr.2021.100087"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-022-01091-x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1309\/ajcphz3cho4huwet"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31434"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0010.7533"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2015.1088649"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-04-848044"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-020-04023-4"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cac2.12241"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T15:58:28Z","timestamp":1692547108000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,26]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/ccr3.7411"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7411","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,5,26]]},"assertion":[{"value":"2023-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7411"}}