{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:08:25Z","timestamp":1753862905784,"version":"3.41.2"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec><jats:title>Key clinical message<\/jats:title><jats:p>Acute anterior uveitis and optic disk edema could be a manifestation of COVID\u201019 infection, and healthcare providers should be aware of this possible consequence for in\u2010time diagnosis and treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Since the beginning of the coronavirus disease\u20102019 (COVID\u201019) pandemic, a wide range of clinical manifestations have been associated with this novel infection. The objective of this study was to show that acute anterior uveitis and optic disk edema could be possible manifestations of COVID\u201019 infection. The patient was a nine\u2010year\u2010old girl presenting with prolonged fever, myalgia, cough, diarrhea, and skin rashes. She also reported blurred vision, Photophobia, and eye redness. PCR test for COVID\u201019 returned positive. Imaging investigations showed pleural and pericardial effusion, mediastinal lymphadenopathy, and heart valve regurgitation. She was diagnosed with MIS\u2010C and treated with methylprednisolone and IVIG. Bilateral acute anterior uveitis and optic disk edema was detected by slit lamp and fundus examination. She was successfully treated and follow\u2010up ophthalmologic examinations showed improvement.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.7473","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T05:50:36Z","timestamp":1686203436000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral acute anterior uveitis and optic nerve edema as a manifestation of coronavirus disease\u20102019 (<scp>COVID<\/scp>\u201019): A case report"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0327-4237","authenticated-orcid":false,"given":"Aria","family":"Mohamadzadeh","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine Razi University  Kermanshah Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1240-3240","authenticated-orcid":false,"given":"Dena","family":"Mohamadzadeh","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Imam Reza Hospital Kermanshah University of Medical Sciences  Kermanshah Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11684-020-0754-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2020.05.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-020-04749-4"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2016.1196713"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.02.019"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_928_20"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.26229"},{"issue":"2","key":"e_1_2_10_9_1","first-page":"234","article-title":"Ocular manifestations of patients with coronavirus disease 2019: a comprehensive review","volume":"16","author":"Roshanshad A","year":"2021","journal-title":"J Ophthalmic Vis Res"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-021-00418-z"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S260252"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S312461"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T16:00:53Z","timestamp":1692547253000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/ccr3.7473"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7473","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"2023-04-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7473"}}