{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:59:25Z","timestamp":1769165965525,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,7,2]],"date-time":"2023-07-02T00:00:00Z","timestamp":1688256000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>Clinicians should be mindful of the rare occurrence of spontaneous bacterial peritonitis in essential thrombocythemia with extensive splanchnic vein thrombosis, especially when patients with ascites exhibit fever and abdominal pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Spontaneous bacterial peritonitis (SBP) complicating extensive splanchnic vein thrombosis (SVT) is a rare manifestation of essential thrombocythemia (ET). In the absence of any hypercoagulable state, JAK2 mutation can be an important risk factor for extensive SVT. Evaluation for SBP is crucial when non\u2010cirrhotic patient exhibits fever, abdominal pain and tenderness in the background of ascites after ruling out common pathologies such as tubercular peritonitis, acute pancreatitis, Budd\u2010Chiari syndrome and ovarian malignancy. We present a case of SBP complicating pre\u2010hepatic portal hypertension with ascites in a 44\u2010years\u2010old female. On further evaluation, extensive SVT with portal cavernoma in the setting of ET was identified. She was managed with cytoreductive therapy and anticoagulation, resulting in symptom resolution.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.7634","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T03:50:40Z","timestamp":1688356240000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Spontaneous bacterial peritonitis complicating extensive splanchnic vein thrombosis, a rare manifestation of essential thrombocythemia: A case report"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6298-1148","authenticated-orcid":false,"given":"Saurav","family":"Agrawal","sequence":"first","affiliation":[{"name":"Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7073-1741","authenticated-orcid":false,"given":"Sandesh","family":"Rayamajhi","sequence":"additional","affiliation":[{"name":"Nepalese Army Institute of Health Sciences College of Medicine  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1130-9006","authenticated-orcid":false,"given":"Aadesh","family":"Rayamajhi","sequence":"additional","affiliation":[{"name":"Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8570-5223","authenticated-orcid":false,"given":"Susmin","family":"Karki","sequence":"additional","affiliation":[{"name":"Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University  Kathmandu 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