{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:05:42Z","timestamp":1754093142843,"version":"3.41.2"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T00:00:00Z","timestamp":1694044800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>Renal aspergillosis is a rare condition and this case the first case of Renal aspergillosis reported after COVID\u201019\u2010associated pulmonary aspergillosis. Renal symptoms should arise clinical suspicion to renal involvement that happened as a result of hematogenous spreading of pulmonary aspergillosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Secondary fungal infections are among the most significant complications that can arise after COVID\u201019 and have the potential to lead to a high rate of morbidity and mortality. As COVID\u201019 primarily involves the airway, the majority of fungal infections reported have been related to the respiratory system. However, renal aspergillosis that we have reported is a rare condition that also can occur. A 67\u2010year\u2010old man was referred to our hospital and admitted as a COVID\u201019 patient. After the initial recovery, he experienced a recurrence of fever accompanied by a productive cough. The histopathological studies were conducted on the sputum and bronchoalveolar lavage samples, which revealed the presence of <jats:italic>Aspergillus flavus<\/jats:italic>. We treated the patient with voriconazole and the patient was discharged after a period of time. However, after approximately 6\u2009months, he returned to the hospital with a fever and abdominal pain. We started a fever workup. Two new hypoechoic abscess\u2010like masses were spotted in the right kidney in the ultrasonography (U\/S) and the direct molecular studies of the biopsy sample obtained under U\/S guidance identified <jats:italic>Aspergillus flavus<\/jats:italic>. Although renal aspergillosis is a rare condition, it should not be overlooked, especially in patients with severe COVID\u201019 and pulmonary aspergillosis, as these conditions can lead to renal aspergillosis, which may present with symptoms such as abdominal pain with fever. Therefore, it is necessary to perform radiological and histopathological studies when renal aspergillosis is suspected.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.7882","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T23:59:47Z","timestamp":1694131187000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Renal aspergillosis after <scp>COVID<\/scp>\u201019\u2010associated pulmonary aspergillosis: A case report"],"prefix":"10.1002","volume":"11","author":[{"given":"Roya","family":"Ghasemian","sequence":"first","affiliation":[{"name":"Department of Infectious Disease Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lale","family":"Vahedi\u00a0Larijani","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine Mazandaran University of Medical Sciences  Sari Iran"},{"name":"Gastrointestinal Cancer Research Center, Non\u2010Communicable Diseases Institute, Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimia","family":"Rasouli","sequence":"additional","affiliation":[{"name":"Student Research Committee, School of Medicine Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Taghi","family":"Hedayati","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology, School of Medicine Mazandaran University of Medical Sciences  Sari Iran"},{"name":"Invasive Fungi Research Center\/Department of Medical Mycology, School of Medicine Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chanour","family":"Tavakol","sequence":"additional","affiliation":[{"name":"Tehran School of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyvan","family":"Heydari","sequence":"additional","affiliation":[{"name":"Gastrointestinal Cancer Research Center, Non\u2010Communicable Diseases Institute, Mazandaran University of Medical Sciences  Sari Iran"},{"name":"Student Research Committee, School of Medicine Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8057-2804","authenticated-orcid":false,"given":"Hamidreza","family":"Zalpoor","sequence":"additional","affiliation":[{"name":"Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences  Shiraz Iran"},{"name":"Network of Immunity in Infection, Malignancy &amp; 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