{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:05:41Z","timestamp":1754093141674,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>Pneumothorax and bronchopleural fistula (BPF) are potentially fatal complications that can occur in patients with COVID\u201019 pneumonia. Early detection, appropriate treatment, and consideration of surgical intervention are necessary for optimum outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><\/jats:sec><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Healthcare professionals face complex challenges as a result of the rare emergence of pneumothorax among the variety of COVID\u201019 complications, including severe viral pneumonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case History<\/jats:title><jats:p>A 57\u2010year\u2010old male with multiple comorbidities diagnosed with COVID\u201019 pneumonia was admitted to our center and exhibited bilateral crepitations. During hospitalization, the patient developed right\u2010sided pneumothorax that persisted despite chest tube insertion was linked to the presence of BPF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The occurrence of pneumothorax in COVID\u201019 patients is relatively rare risk factors for which are not yet fully understood, although smoking history may play a role. Conservative management is recommended for asymptomatic cases, while intercostal drainage is necessary for symptomatic patients. Surgical intervention may be required to manage the BPF in some instances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pneumothorax and BPF are rare but potentially life\u2010threatening complications in patients recovering from COVID\u201019 pneumonia. Early recognition, appropriate treatment, and consideration of surgical intervention are crucial for optimizing patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.7989","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T01:48:34Z","timestamp":1695692914000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bronchopleural fistula associated persistent pneumothorax in a patient recovering from <scp>COVID<\/scp>\u201019 pneumonia: A case report"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1331-918X","authenticated-orcid":false,"given":"Milan","family":"Regmi","sequence":"first","affiliation":[{"name":"Tribhuvan University Institute of Medicine  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anurag","family":"Karki","sequence":"additional","affiliation":[{"name":"Tribhuvan University Institute of Medicine  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7910-6793","authenticated-orcid":false,"given":"Moon","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Tribhuvan University Institute of Medicine  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nibesh","family":"Pathak","sequence":"additional","affiliation":[{"name":"Tribhuvan University Institute of Medicine  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Tribhuvan University Institute of Medicine  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niraj Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Tribhuvan University Institute of Medicine  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pankaj","family":"Pant","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine Institute of Medicine Tribhuvan University Teaching Hospital  Maharajgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-020-01457-w"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2020.05.012"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2020.0180"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/23247096211013215"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000135932"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2021.04.005"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.5.1279"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2020.09.026"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.58.suppl_2.ii39"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.5149"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.5128"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7989","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T05:56:30Z","timestamp":1754027790000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7989"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1002\/ccr3.7989"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7989","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"2023-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7989"}}