{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:24:38Z","timestamp":1764253478868,"version":"3.46.0"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Key Clinical Message<\/jats:title>\n                    <jats:p>Electrical Impedimetric Tumor Detection System is a novel and promising tool for fast intraoperative tumor delineation and accurate safe margin detection in orbital tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Adenoid cystic carcinoma (ACC) is a rare malignant tumor of epithelial origin, typically arising from the salivary and lacrimal glands. ACC is notorious for recurrence and a high rate of morbidity and mortality despite therapy. We presented a 48\u2010year\u2010old male patient with lacrimal gland ACC of the right orbit who underwent radical tumor resection and adjuvant radiotherapy. We applied a new diagnostic method, the Electrical Impedimetric Tumor Detection System, during surgery and tested its performance to enhance the precision of tumor resection. Two months after surgery, he underwent external radiation of 58\u2009Gy in 29 fractions. He showed no tumor recurrence or metastasis in the 1\u2010year follow\u2010up visits. ITDS showed a precision of tumor and margin detection consistent with histopathology results. This novel ITDS may be a reliable system for fast intraoperative tumor delineation and accurate, safe margin detection in orbital tumors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.7995","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T01:40:45Z","timestamp":1696902045000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intraoperative use of electrical impedance spectroscopy for adenoid cystic carcinoma of the lacrimal gland: A case report"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0770-0654","authenticated-orcid":false,"given":"Mohammad Reza","family":"Fattahi","sequence":"first","affiliation":[{"name":"Student Research Committee, School of Advanced Technologies in Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"},{"name":"Department of Surgical Oncology, Cancer Institute Tehran University of Medical Sciences  Tehran Iran"},{"name":"UT and TUMS Cancer Electronics Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3772-0349","authenticated-orcid":false,"given":"Mohammadkian","family":"Zarafshani","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Cancer Institute Tehran University of Medical Sciences  Tehran Iran"},{"name":"Cancer Biology Research Center, Cancer Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Abdolahad","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Cancer Institute Tehran University of Medical Sciences  Tehran Iran"},{"name":"UT and TUMS Cancer Electronics Research Center Tehran University of Medical Sciences  Tehran Iran"},{"name":"Nano Electronic Center of Excellence, Nano\u2010bioelectronic Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, College of Engineering University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amirmohsen","family":"Jalaeefar","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Cancer Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reihane","family":"Mahdavi","sequence":"additional","affiliation":[{"name":"Nano Electronic Center of Excellence, Nano\u2010bioelectronic Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, College of Engineering University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narges","family":"Yousefpour","sequence":"additional","affiliation":[{"name":"Nano Electronic Center of Excellence, Nano\u2010bioelectronic Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, College of Engineering University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Saffar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Imam Khomeini Hospital Center, Cancer Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Mohamad Sadegh","family":"Mousavi\u2010Kiasary","sequence":"additional","affiliation":[{"name":"Nano Electronic Center of Excellence, Nano\u2010bioelectronic Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, College of Engineering University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7392-6056","authenticated-orcid":false,"given":"Farzad","family":"Pakdel","sequence":"additional","affiliation":[{"name":"Department of Oculofacial Plastic Surgery, Farabi Hospital Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000033446"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2022.107623"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2015.10.002"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000877"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199606000-00008"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15123211"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14812"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000531"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2012.02402.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3857\/roj.2021.00122"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.10259"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112421"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mp.15481"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2021.106166"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.08.048"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3054.2003.00086.x"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:21:12Z","timestamp":1764253272000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/ccr3.7995"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7995","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"2023-05-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7995"}}