{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:25:04Z","timestamp":1764253504577,"version":"3.46.0"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T00:00:00Z","timestamp":1696291200000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Key Clinical Message<\/jats:title>\n                  <jats:p>This case report documents the unusual co\u2010occurrence of immune thrombocytopena (ITP) and chickenpox in a 15\u2010year\u2010old girl. Initial symptoms included shortness of breath, chest pain, and heavy menstrual bleeding. Laboratory results revealed significant anemia and thrombocytopenia. Treatment involved blood transfusions, prednisolone, and iron supplementation. The patient's vesicular skin rash emerged 8\u2009weeks later, prompting the combined diagnosis of ITP and chickenpox. Antiviral treatments, blood transfusions, and supportive care were used in the course of treatment, leading to full recovery. This case emphasizes the importance of prompt diagnosis, appropriate management, and regular follow\u2010up for patients with both chickenpox and ITP. The coexistence of chickenpox and ITP poses a clinical challenge due to the complex interaction between the viral infection and the immune system. The exact mechanism linking these two conditions remains unclear, making it a baffling case that warrants investigation and further understanding. As low is the occurrence of hemorrhagic chickenpox, the presentation of simultaneous chicken pox with or following ITP was found to be rarer, and thus is this enigmatic case presented. Healthcare providers should remain vigilant about such co\u2010occurrences to prevent complications. In order to improve treatment for instances with comparable clinical presentations and advance our collective knowledge, further study is required to better understand the mechanisms relating viral infections and ITP.<\/jats:p>","DOI":"10.1002\/ccr3.8014","type":"journal-article","created":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:15:30Z","timestamp":1696378530000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Parallel pathogens: Coexistence of chickenpox and idiopathic thrombocytopenic purpura\u2014A case report"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0681-3825","authenticated-orcid":false,"given":"Abhigan Babu","family":"Shrestha","sequence":"first","affiliation":[{"name":"M Abdur Rahim Medical College Hospital  Dinajpur Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuj","family":"Yadav","sequence":"additional","affiliation":[{"name":"M Abdur Rahim Medical College Hospital  Dinajpur Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadish","family":"Sharma","sequence":"additional","affiliation":[{"name":"College of Medical Sciences  Bharatpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Unnat Hamal","family":"Sapkota","sequence":"additional","affiliation":[{"name":"M Abdur Rahim Medical College Hospital  Dinajpur Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3277-2270","authenticated-orcid":false,"given":"Mohamad Ali","family":"Farho","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Aleppo  Aleppo Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. 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Ibn","family":"Abu\u00a0Sayem","sequence":"additional","affiliation":[{"name":"M Abdur Rahim Medical College Hospital  Dinajpur Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md.","family":"Nuruzzaman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine M\u00a0Abdur Rahim Medical College Hospital  Dinajpur Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.32677\/IJCH.2017.v04.i04.044"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000966"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2009.11.004"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-013-1217-2"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.04131.x"},{"key":"e_1_2_12_7_1","first-page":"27","article-title":"Childhood immune thrombocytopenia: clinical presentation and management, Sudan","volume":"12","author":"Faki Osman ME","year":"2012","journal-title":"J Paediatr"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.16"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/172.3.706"},{"key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.13112\/pc.468","article-title":"A case of chickenpox with complication of post\u2010infectious thrombocytopenic purpura","volume":"63","author":"Ivanovich SO","year":"2019","journal-title":"Paedia croat"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM194708142370704"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-162503"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.15406\/mojcr.2021.11.00379"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6020016"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1996.d01-1872.x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.04.032"},{"key":"e_1_2_12_17_1","first-page":"756","article-title":"Clinical practice updates in the management of immune thrombocytopenia","volume":"42","author":"Khan AM","year":"2017","journal-title":"P T"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/08916930802198436"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12314"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/aian.aian_270_21"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:22:07Z","timestamp":1764253327000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/ccr3.8014"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8014","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"2023-06-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ccr3.8014"}}