{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T17:19:29Z","timestamp":1788974369155,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:00:00Z","timestamp":1697673600000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Key Clinical Message<\/jats:title>\n                  <jats:p>Immunocompromised district refers to the area of the skin with altered immune response predisposing secondary diseases to develop in an immunocompetent individual. This might be explained by the theory of T\u2010cell exhaustion which is characterized by the impairment of the effector function of antigen\u2010specific T cells due to chronic persistence of the primary antigen. T\u2010cell exhaustion model is not well known; however, it serves as a newer concept in the pathogenesis of diseases occurring simultaneously over the same site. Thus, it is not surprising to have two different infectious or non\u2010infectious dermatoses over the same site one preceding the other as observed in our patient. The concept of immunocompromised district and T\u2010cell exhaustion is a rare phenomenon; however, it should be identified by the treating physicians\/dermatologists for the optimum management of the atypical presentation of the diseases.<\/jats:p>","DOI":"10.1002\/ccr3.8067","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T03:00:37Z","timestamp":1697770837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Herpes zoster occurring over the site of tinea cruris\u2014A case report based on the model of T\u2010cell exhaustion in the Ruocco's\u00a0immunocompromised cutaneous\u00a0district"],"prefix":"10.1002","volume":"11","author":[{"given":"Mahesh","family":"Mathur","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology, and Leprology College of Medical Sciences and Teaching Hospital  Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Thakur","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Leprology College of Medical Sciences and Teaching Hospital  Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3905-5247","authenticated-orcid":false,"given":"Sunil","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Leprology College of Medical Sciences and Teaching Hospital  Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srijana","family":"Maharjan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Leprology College of Medical Sciences and Teaching Hospital  Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2177-8995","authenticated-orcid":false,"given":"Supriya","family":"Paudel","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Leprology College of Medical Sciences and Teaching Hospital  Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjali","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Leprology College of Medical Sciences and Teaching Hospital  Bharatpur Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14810"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.174422"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3215"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijdvl.IJDVL_1021_16"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.5483\/BMBRep.2011.44.4.217"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2010.03255.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12470582"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40588-016-0044-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02878.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.25259\/IJDVL_1412_20"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8067","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:22:57Z","timestamp":1764253377000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/ccr3.8067"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8067","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"2023-08-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8067"}}