{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:35:59Z","timestamp":1761845759685,"version":"3.41.2"},"reference-count":11,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T00:00:00Z","timestamp":1700352000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Key Clinical Message<\/jats:title><jats:p>Lysozyme\u2010induced nephropathy is a rare form of acute tubular injury that has almost exclusively been reported in patients with monocytic malignancies. Typically, patients will present in acute renal failure A renal biopsy is necessary to confirm the diagnosis and will demonstrate proximal tubular cells with hypereosinophilic granules, which are periodic acid\u2010Schiff and Jones methenamine silver\u2010positive. Immunohistochemical staining for lysozyme will also be present. The following rare case will describe a case of lysozyme nephropathy in a patient without any underlying hematological malignancy, but instead with systemic granulomatous disease.<\/jats:p>","DOI":"10.1002\/ccr3.8122","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T06:00:45Z","timestamp":1700460045000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>Lysozyme\u2010induced<\/scp> nephropathy due to systemic granulomatous disease"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7968-8240","authenticated-orcid":false,"given":"Hamza","family":"Ashraf","sequence":"first","affiliation":[{"name":"Overlook Medical Center Atlantic Health System  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6059-5796","authenticated-orcid":false,"given":"Dariusz","family":"Uczkowski","sequence":"additional","affiliation":[{"name":"Overlook Medical Center Atlantic Health System  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Stuart","sequence":"additional","affiliation":[{"name":"Overlook Medical Center Atlantic Health System  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-386483-3.00003-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/38.12.1249"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmb.21092"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2016.09.002"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annpat.2020.04.001"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2023.05.007"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.34344"},{"issue":"9","key":"e_1_2_10_9_1","first-page":"407","article-title":"Progressive kidney failure in chronic myelomonocytic leukaemia: don't forget lysozyme damage","volume":"76","author":"Hillen JM","year":"2018","journal-title":"Neth J Med"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2015.22.75.6237"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/pl00007637"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-016-0194-4"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T05:21:28Z","timestamp":1702444888000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":11,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1002\/ccr3.8122"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8122","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"2023-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8122"}}