{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T13:09:22Z","timestamp":1766754562512,"version":"3.41.2"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,11]]},"abstract":"Key Clinical Message<\/jats:title>This case report highlights the importance of recognizing and accurately diagnosing ganglioneuroblastoma, an uncommon variant of neuroblastic tumors in children. Ganglioneuroblastomas have diverse clinical and morphological presentations, and histopathological examination is paramount in guiding treatment decisions, especially in cases with ambiguous symptoms. Early detection is crucial, as the prognosis varies significantly based on the subtype and the presence of metastatic disease. Clinicians should maintain a high index of suspicion and utilize radiological examinations to promptly identify and treat these tumors.<\/jats:p><\/jats:sec>Abstract<\/jats:title>Children are frequently affected by neuroblastic tumors, which grow from the sympathoadrenal lineage of the neural crest during its development. However, intermixed ganglioneuroblastomas are far less common within the same tumor spectrum, the diagnosis of which could become challenging amidst an unusual presentation. In our case report, we present a 4\u2010year\u2010old boy who had complaints of fever and difficulty in walking, with a supra\u2010renal mass on ultrasound, which was diagnosed as ganglioneuroblastoma\u2010intermixed type on histopathological examination. This report aims to contribute to the understanding of the diverse clinical and morphological spectrum of ganglioneuroblastomas and the importance of multidisciplinary collaboration and histopathological examination to enhance decision\u2010making in such ambiguous scenarios.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.8149","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T14:53:40Z","timestamp":1700751220000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A needle in the haystack: An unusual case presentation of ganglioneuroblastoma at a tertiary care center in Coastal Karnataka"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3407-6030","authenticated-orcid":false,"given":"Shalini","family":"Radhakrishnan","sequence":"first","affiliation":[{"name":"Department of Pathology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9786-0485","authenticated-orcid":false,"given":"Ranjitha","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Pathology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6398-6546","authenticated-orcid":false,"given":"Harsha Prasada","family":"Lashkari","sequence":"additional","affiliation":[{"name":"Department of Paediatric Haematology and Oncology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0803-6692","authenticated-orcid":false,"given":"Hema","family":"Kini","sequence":"additional","affiliation":[{"name":"Department of Pathology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3351-9517","authenticated-orcid":false,"given":"Jyoti Ramnath","family":"Kini","sequence":"additional","affiliation":[{"name":"Department of Pathology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8926-9289","authenticated-orcid":false,"given":"Vatsala Basavaraju","family":"Kudurugundi","sequence":"additional","affiliation":[{"name":"Department of Pathology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanishree","family":"Ashok","sequence":"additional","affiliation":[{"name":"Kasturba Medical College Mangalore, Jyothi Circle Mangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5906-5197","authenticated-orcid":false,"given":"Chaithra Venkataramana","family":"Gowthuvalli","sequence":"additional","affiliation":[{"name":"Department of Pathology Kasturba Medical College Mangalore, Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,22]]},"reference":[{"volume-title":"WHO Classification of Tumours Editorial Board. 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