{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T10:17:54Z","timestamp":1775557074687,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T00:00:00Z","timestamp":1700092800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,11]]},"abstract":"Key Clinical Message<\/jats:title>Tuberculous myocarditis is a rare presentation of tuberculosis, posing diagnostic challenges in endemic countries. Clinicians should consider this entity in patients with unexplained heart failure, conduction abnormalities, or sudden cardiac events in tuberculosis\u2010endemic regions.<\/jats:p><\/jats:sec>Abstract<\/jats:title>Tuberculous myocarditis is an uncommon manifestation of tuberculosis, often presenting as a diagnostic challenge, particularly in tuberculosis\u2010endemic regions. We report a case of a 58\u2010year\u2010old male with a history of chronic cough and fever, who presented with progressive dyspnea, generalized body swelling, and New York Heart Association (NYHA) Class IV heart failure. Clinical examination revealed signs of cardiac decompensation and congestive heart failure. Emergency echocardiography demonstrated biventricular dysfunction, and imaging showed clots in both atria and the left ventricle. The patient responded well to initial treatment with anticoagulants, antibiotics, diuretics, and inotropic support. Subsequent investigations, including computed tomography pulmonary angiogram (CTPA) and high\u2010resolution computed tomography (HRCT), confirmed active pulmonary tuberculosis. Anti\u2010tuberculous treatment (ATT) was initiated, and the patient showed remarkable improvement. The diagnosis of tuberculous myocarditis was based on clinical, radiological, and laboratory evidence, as cardiac biopsy was not performed due to resource limitations. Tuberculous myocarditis is an underreported condition, and clinicians should be vigilant about its occurrence, especially in tuberculosis\u2010endemic regions. Early recognition and prompt initiation of ATT can lead to favorable outcomes. This case highlights the importance of considering tuberculous myocarditis in patients with unexplained heart failure or cardiac abnormalities in areas with a high burden of tuberculosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.8224","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T08:07:00Z","timestamp":1700208420000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A rare case of tuberculous myocarditis: A diagnostic challenge in a tuberculosis\u2010endemic country"],"prefix":"10.1002","volume":"11","author":[{"given":"Ghulam Abbas","family":"Shaikh","sequence":"first","affiliation":[{"name":"Department of Cardiology Dr. Ruth K. M. Pfau, Civil Hospital Karachi Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samina","family":"Yaqoob","sequence":"additional","affiliation":[{"name":"Department of Cardiology Dr. Ruth K. M. Pfau, Civil Hospital Karachi Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fareeha","family":"Batool","sequence":"additional","affiliation":[{"name":"Department of Cardiology Dr. Ruth K. M. Pfau, Civil Hospital Karachi Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1071-8476","authenticated-orcid":false,"given":"Radeyah","family":"Waseem","sequence":"additional","affiliation":[{"name":"Dow University of Health Sciences Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8032-7462","authenticated-orcid":false,"given":"Hussain Haider","family":"Shah","sequence":"additional","affiliation":[{"name":"Dow University of Health Sciences Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asim Ali","family":"Abbasi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Dr. Ruth K. M. Pfau, Civil Hospital Karachi Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nawaz","family":"Lashari","sequence":"additional","affiliation":[{"name":"Department of Cardiology Dr. Ruth K. M. Pfau, Civil Hospital Karachi Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7935-7333","authenticated-orcid":false,"given":"Tirth","family":"Dave","sequence":"additional","affiliation":[{"name":"Bukovinian State Medical University Chernivtsi Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0163-4453(96)80023-5"},{"key":"e_1_2_11_3_1","first-page":"422","article-title":"Cardiac tuberculosis. A study of 19 patients","volume":"111","author":"Rose AG","year":"1987","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2015.21.118.4282"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268822000358"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.02.107"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.22715"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.5.2006"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1530\/ERP-17-0024"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.019435"},{"issue":"3","key":"e_1_2_11_11_1","first-page":"169","article-title":"Concomitant endobronchial tuberculosis, myocarditis and congestive heart failure","volume":"47","author":"Agarwal N","year":"2000","journal-title":"Indian J Tuberc"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10085-4211"},{"key":"e_1_2_11_13_1","first-page":"49","article-title":"Tuberculosis and dilated cardiomyopathy\u2010case report of a rare entity with literature review","volume":"3","author":"Barman B","year":"2015","journal-title":"Am J Med Case Rep"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht210"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.584532"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T05:23:20Z","timestamp":1702445000000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1002\/ccr3.8224"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8224","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"2023-08-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8224"}}