{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:08:16Z","timestamp":1753862896512,"version":"3.41.2"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>Bullous pemphigoid did not follow the course of Gastric Carcinoma relapse and remisson, unlike the malignant acanthosis nigricans which was in alignment with the paraneoplastic effect of the Gastric Carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Acanthosis nigricans (AN) is a dermatosis characterized by the presence of hyperpigmented, velvety cutaneous thickening in the flexural areas, posterior neck, and occasionally the extensor surfaces of hand, face, and oral mucosa. AN is commonly associated with insulin resistance, drugs, and rarely internal malignancy (malignant AN). Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by tense blisters involving the skin of mainly elderly patients. The association of BP and malignancy is not well established and the co\u2010existence of BP with AN has not been reported. Here we report a 58\u2010year\u2010old, event\u2010free gastric adenocarcinoma with three types of skin findings with different pathogenesis\u2010 BP, malignant AN, and erysipelas\u2010like metastasis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.8351","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T04:29:01Z","timestamp":1704256141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bullous pemphigoid, malignant acanthosis nigricans, and erysipeloid carcinoma in a woman with gastric adenocarcinoma"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7324-0347","authenticated-orcid":false,"given":"Saman","family":"Al\u2010Zahawi","sequence":"first","affiliation":[{"name":"Department of Dermatology Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9213-6420","authenticated-orcid":false,"given":"Yasaman","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vahidesadat","family":"Azhari","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamidreza","family":"Mahmoudi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"},{"name":"Autoimmune Bullous Diseases Research Center Razi Hospital Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Daneshpazhooh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"},{"name":"Autoimmune Bullous Diseases Research Center Razi Hospital Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,2]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","first-page":"26","article-title":"Epidemiology of gastric cancer: global trends, risk factors and prevention","volume":"14","author":"Rawla P","year":"2019","journal-title":"Prz Gastroenterol"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.4372"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-013-1399-5"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2014.5263"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1983.01650320078022"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.135493"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12764"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-020-01708-2"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.4322\/acr.2016.021"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S290124"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02159.x"},{"issue":"10","key":"e_1_2_11_13_1","first-page":"910","article-title":"Metastatic carcinoma of cervix with acanthosis nigricans, bullous pemphigoid and hypertrophic pulmonary osteoarthropathy","volume":"56","author":"Ive F","year":"1963","journal-title":"Proc R Soc Med"},{"volume-title":"Acanthosis nigricans","year":"2017","author":"Brady MF","key":"e_1_2_11_14_1"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-228418"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T03:55:02Z","timestamp":1706846102000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/ccr3.8351"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8351","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8351"}}