{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:30:32Z","timestamp":1764253832032,"version":"3.46.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Key clinical message<\/jats:title>\n                    <jats:p>Struma ovarii (SO), is a rare and specialized ovarian teratoma. The treatment is controversial depending on the risk of recurrence and metastasis. Here a SO with papillary thyroid carcinoma is reported and the approach is thoroughly discussed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Struma ovarii (SO) is a highly specialized ovarian teratoma primarily composed of thyroid tissue. Clinical features associated with SO include lower abdominal discomfort, unusual vaginal bleeding, ascites, and hyperthyroidism. While SO rarely transforms into malignancy, the optimal degree of treatment remains controversial due to the varying risks of recurrence and metastasis. In this report, we present the case of a 64\u2010year\u2010old woman experiencing abdominal pain and diagnosed with SO, accompanied by papillary thyroid carcinoma. We thoroughly discuss the evaluation and management of this rare condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.8610","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T22:00:01Z","timestamp":1712959201000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A case report of malignant struma ovarii with papillary thyroid carcinoma"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6156-3136","authenticated-orcid":false,"given":"Yekta","family":"Rahimi","sequence":"first","affiliation":[{"name":"University of Southern California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soghra","family":"Rabizadeh","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali\u2010Asr Hospital Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Seifouri","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiana","family":"Seifouri","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali\u2010Asr Hospital Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samane","family":"Salarvand","sequence":"additional","affiliation":[{"name":"Department of pathology Cancer Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9744-2328","authenticated-orcid":false,"given":"Manouchehr","family":"Nakhjavani","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali\u2010Asr Hospital Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.3802\/jgo.2008.19.2.135"},{"doi-asserted-by":"publisher","key":"e_1_2_10_3_1","DOI":"10.1089\/thy.2011.0162"},{"doi-asserted-by":"publisher","key":"e_1_2_10_4_1","DOI":"10.3389\/pore.2022.1610221"},{"doi-asserted-by":"publisher","key":"e_1_2_10_5_1","DOI":"10.5858\/134.5.786"},{"doi-asserted-by":"publisher","key":"e_1_2_10_6_1","DOI":"10.1159\/000108654"},{"doi-asserted-by":"publisher","key":"e_1_2_10_7_1","DOI":"10.25179\/tjem.2021-81052"},{"issue":"2","key":"e_1_2_10_8_1","first-page":"263","article-title":"Struma ovarii: hyperthyroidism in a postmenopausal woman","volume":"29","author":"March DE","year":"1988","journal-title":"J Nucl Med"},{"issue":"5","key":"e_1_2_10_9_1","first-page":"748","article-title":"Clinical diversity of struma ovarii","volume":"45","author":"Kim S\u2010J","year":"2002","journal-title":"Korean J Obstet Gynecol"},{"doi-asserted-by":"publisher","key":"e_1_2_10_10_1","DOI":"10.1016\/S0090-8258(03)00141-0"},{"issue":"6","key":"e_1_2_10_11_1","first-page":"296","article-title":"Occult thyroid carcinoma","volume":"29","author":"Boucek J","year":"2009","journal-title":"Acta Otorhinolaryngol Ital"},{"doi-asserted-by":"publisher","key":"e_1_2_10_12_1","DOI":"10.1097\/PGP.0b013e3181bfb133"},{"doi-asserted-by":"publisher","key":"e_1_2_10_13_1","DOI":"10.1007\/s12558-015-0364-y"},{"doi-asserted-by":"publisher","key":"e_1_2_10_14_1","DOI":"10.1186\/s12957-016-0776-x"},{"doi-asserted-by":"publisher","key":"e_1_2_10_15_1","DOI":"10.1006\/gyno.2001.6315"},{"doi-asserted-by":"publisher","key":"e_1_2_10_16_1","DOI":"10.1097\/PAS.0b013e31802f5404"},{"doi-asserted-by":"publisher","key":"e_1_2_10_17_1","DOI":"10.1007\/BF03033726"},{"doi-asserted-by":"publisher","key":"e_1_2_10_18_1","DOI":"10.1097\/00004347-199310000-00008"},{"doi-asserted-by":"publisher","key":"e_1_2_10_19_1","DOI":"10.1186\/s13256-022-03590-6"},{"doi-asserted-by":"publisher","key":"e_1_2_10_20_1","DOI":"10.1136\/bmjdrc-2020-001443"},{"key":"e_1_2_10_21_1","first-page":"11","article-title":"The clinical and pathological characteristics of malignant struma ovarii: an analysis of 144 published patients. 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