{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:19:35Z","timestamp":1783113575934,"version":"3.54.6"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Key Clinical Message<\/jats:title>\n                    <jats:p>The mainstays of treatment for granuloma pyogenicum include careful evaluation of any penile growth, thorough excision of the polypoid, histological examination, and close monitoring to check relapse and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Pyogenic granuloma is an acquired noncancerous vascular proliferation that arises from the mucosa and skin, seldom subcutaneously or intravascularly. It is also referred to as telangiectasis granuloma or lobular capillary haemangioma. The risk factors include vascular abnormalities, medicines, hormones, and microtrauma. We discussed the case of a 24\u2010year\u2010old man who had a poorly managed ventral distal penile polypoid lesion at a peripheral hospital. Upon further histopathological examination, the diagnosis of pyogenic granuloma was made. Histopathologically speaking, the term \u201cpyogenic granuloma\u201d is misleading because the illness is not linked to the production of granulomas. Pyogenic granuloma's etiopathogenesis is still unknown; true hemangioma is thought to be a reactive hyperproliferative of the vasculature brought on by a variety of stimuli; pyogenic granuloma may be caused by uneven angiogenic factor production in response to minor local trauma or cutaneous disease. Histopathological analysis and surgical excision are the methods used for diagnosis and treatment. The mainstay of treatment for granuloma pyogenic granuloma includes careful evaluation of any penile growth, thorough excision of the polypoid, histological examination, close follow\u2010up to check for relapse, and early management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.8659","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T22:55:49Z","timestamp":1709938549000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Distal penile pyogenic granuloma: A case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2920-2767","authenticated-orcid":false,"given":"Gideon Safiel","family":"Mwasakyalo","sequence":"first","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Bright","sequence":"additional","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6689-3452","authenticated-orcid":false,"given":"Orgenes Jasper","family":"Mbwambo","sequence":"additional","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bartholomeo Nicholaus","family":"Ngowi","sequence":"additional","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Mwakibibi","sequence":"additional","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasper Saidi","family":"Mbwambo","sequence":"additional","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa Raymond","family":"Majura","sequence":"additional","affiliation":[{"name":"Department of Urology Kilimanjaro Christian Medical Centre  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evans Azina","family":"Sanga","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Critical care Ministry of Health Social Services (hMOHSS) District Hospital Keetmanshoop  Kharas Namibia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7226-0168","authenticated-orcid":false,"given":"Alex","family":"Mremi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"},{"name":"Department of Pathology Kilimanjaro Christian Medical Centre  Moshi Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"issue":"9","key":"e_1_2_12_2_1","first-page":"1","article-title":"Multiple pyogenic granuloma of the penis in a four\u2010year\u2010old child: a case report","volume":"2","author":"Spinelli C","year":"2009","journal-title":"Cases 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