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Here we present a case study of a 58\u2010year\u2010old female patient who presented with generalized weakness, abdominal discomfort, and per\u2010rectal bleeding. This case report highlights the importance of understanding the histopathological features of serrated adenocarcinoma for accurate diagnosis which has impact on further management.<\/jats:p>","DOI":"10.1002\/ccr3.8669","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T23:34:41Z","timestamp":1710891281000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Serrated adenocarcinoma of sigmoid colon with mismatch repair protein\u2010proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma"],"prefix":"10.1002","volume":"12","author":[{"given":"Diksha","family":"Karki","sequence":"first","affiliation":[{"name":"Department of Pathology Bhaktapur Cancer Hospital  Bhaktapur Bagmati Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7483-3530","authenticated-orcid":false,"given":"Sajan","family":"Ngakhusi","sequence":"additional","affiliation":[{"name":"Department of Pathology Bhaktapur Cancer Hospital  Bhaktapur Bagmati Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"International Agency for Research on Cancer.World Health Organisation.2021.https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/935\u2010asia\u2010fact\u2010sheets.pdf"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2006.02548.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00313029209068874"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2010.04.002"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11010164"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.65"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1850"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH800>3.0.CO;2-2"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310456"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200301000-00008"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8669","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.8669","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8669","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:40:52Z","timestamp":1783111252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8669"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1002\/ccr3.8669"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8669","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2023-08-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8669"}}