{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:51:15Z","timestamp":1780102275618,"version":"3.54.0"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T00:00:00Z","timestamp":1712793600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Key Clinical Message<\/jats:title>\n                    <jats:p>Although the concurrent occurrence of vasculitis with AS is uncommon, when patients diagnosed with AS exhibit symptoms including skin petechiae, purpura, abdominal discomfort, malaise, elevated ESR, and reduced complement levels, vigilant monitoring for vasculitis is advisable following the exclusion of secondary vasculitis triggers such as malignancies, infections, and pharmaceutical agents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>The primary characteristic of ankylosing spondylitis (AS) involves inflammation occurring within the sacroiliac joint and the spine, leading to destruction and eventual ankylosis. A notably infrequent complication associated with AS is vasculitis, with limited reports linking AS to vasculitis. This case study documents a 48\u2010year\u2010old male, diagnosed with HLA\u2010B27\u2010positive AS for the past 15\u2009years, who developed abdominal pain and skin lesions following the cessation of his medication on his own. Subsequent clinical evaluations identified leukocytoclastic vasculitis (LCV) related to AS after excluding all other potential causes of LCV, including drug\u2010related sources, cancer, hepatitis B and C viruses, Henoch\u2010Sch\u00f6nlein purpura (HSP), and IgA nephropathy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.8769","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:54:40Z","timestamp":1712883280000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Leukocytoclastic vasculitis in a patient with ankylosing spondylitis: A case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9482-6967","authenticated-orcid":false,"given":"Alireza","family":"Khabbazi","sequence":"first","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences  Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2635-5793","authenticated-orcid":false,"given":"Sepideh Tahsini","family":"Tekantapeh","sequence":"additional","affiliation":[{"name":"Student Research Committee Tabriz University of Medical Sciences, Department of Rheumatology  Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrus","family":"Asadzadeh","sequence":"additional","affiliation":[{"name":"Student Research Committee Tabriz University of Medical Science  Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Vahedi","sequence":"additional","affiliation":[{"name":"Department of Pathology Tabriz University of Medical Science  Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-021-00625-y"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22831"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13242"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000348240"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000014121"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4322\/acr.2018.070"},{"key":"e_1_2_12_8_1","article-title":"Leukocytoclastic vasculitis in a patient with ankylosing spondylitis","volume":"5","author":"Kobak S","year":"2014","journal-title":"Case Rep Rheumatol"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.2340\/0001555577324"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket125"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8769","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:27:16Z","timestamp":1764253636000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1002\/ccr3.8769"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8769","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2024-02-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8769"}}