{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:31:16Z","timestamp":1764253876609,"version":"3.46.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,4]]},"abstract":"\n Key Clinical Message<\/jats:title>\n Osteoblastoma of the frontal sinus, although rare, can manifest with seizures and pneumocephalus, underscoring the importance of thorough evaluation and complete surgical excision to prevent serious complications and ensure optimal patient outcomes.<\/jats:p>\n <\/jats:sec>\n \n Abstract<\/jats:title>\n Osteoblastoma is an infrequent bone tumor, with origins typically in the vertebrae and long bones. While craniofacial involvement is rare, it may occur in regions such as the paranasal sinuses. We present a case of osteoblastoma located in the frontal sinus, an exceptionally uncommon site, resulting in seizures secondary to pneumocephalus. A 21\u2010year\u2010old male presented with a generalized tonic\u2013clonic seizure and postictal confusion. Imaging studies revealed a well\u2010defined lesion in the left frontal sinus causing cortical breach, destruction of the posterior wall, and pneumocephalus. A total surgical excision was performed through bifrontal craniotomy. Histopathological analysis confirmed the diagnosis of osteoblastoma. Postoperative recovery was uneventful, with a follow\u2010up CT scan showing complete lesion excision. Osteoblastomas, especially in the cranial sinuses, are rare entities that may present asymptomatically but can lead to severe complications. The risk of recurrence underscores the importance of complete surgical resection for optimal patient outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ccr3.8776","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T06:48:47Z","timestamp":1713163727000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Osteoblastoma of the frontal sinus: A rare case presenting with seizures and pneumocephalus"],"prefix":"10.1002","volume":"12","author":[{"given":"Dattatraya","family":"Mallik","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Sakra World Hospital Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandyal","family":"Chandrashekhar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Sakra World Hospital Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek Kumar","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Sakra World Hospital Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saransh","family":"Dhingra","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Sakra World Hospital Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Sakra World Hospital Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sapan","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Sakra World Hospital Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9465-2506","authenticated-orcid":false,"given":"Gianluca","family":"Scalia","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Department of Head and Neck Surgery Garibaldi Hospital Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8392-2072","authenticated-orcid":false,"given":"Bipin","family":"Chaurasia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Neurosurgery Clinic Birgunj Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.55418\/188104193X"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-006-0269-z"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3941\/jrcr.v4i6.387"},{"issue":"13","key":"e_1_2_13_5_1","first-page":"1891","article-title":"A rare location of benign osteoblastoma: case study and a review of the literature","volume":"16","author":"Caltabiano R","year":"2012","journal-title":"Eur Rev Med Pharmacol Sci"},{"volume-title":"Bone tumors","year":"1998","author":"Dorfman HD","key":"e_1_2_13_6_1"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-195436030-00011"},{"volume-title":"Bone Tumors. Diagnosis, Treatment and Prognosis","year":"1991","author":"Huvos AG","key":"e_1_2_13_8_1"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(94)90267-4"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(90)90064-9"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01411121"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800580818"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100109569"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.182.5.1821343"},{"key":"e_1_2_13_15_1","first-page":"121","volume-title":"General Aspects and Data on 11,087 Cases","author":"Unni KK","year":"1996"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-5898(20)32101-5"},{"key":"e_1_2_13_17_1","first-page":"215","article-title":"Border line osteoblastic tumors: problems in the differential diagnosis of aggressive osteoblastoma and low\u2010grade osteosarcoma","volume":"1","author":"Dorfman HD","year":"1984","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199704)28:4<304::AID-MPO11>3.0.CO;2-C"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21105"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000061"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.8776","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:27:24Z","timestamp":1764253644000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.8776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1002\/ccr3.8776"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.8776","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2024-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8776"}}