{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:09:11Z","timestamp":1753862951354,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>Timely recognition of atypical Takayasu arteritis is crucial. Unusual presentations, such as pericardial effusion, can complicate diagnosis. CT angiogram aids in precise diagnosis, guiding targeted immunosuppressive therapy. Multidisciplinary collaboration is vital for comprehensive management, improving patient outcomes in this challenging condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>This case study highlights the diagnostic challenges posed by atypical presentations of Takayasu arteritis (TA), focusing on a 42\u2010year\u2010old male presenting with pericardial effusion. Despite inconclusive initial investigations, a CT angiogram revealed large vessel vasculitis, confirming TA. Management with immunosuppressive therapy led to clinical improvement. This case emphasize the importance of recognizing unusual manifestations of TA for timely diagnosis and appropriate treatment, emphasizing the role of multidisciplinary collaboration in optimizing patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9051","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T03:39:57Z","timestamp":1717472397000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unusual manifestations of Takayasu arteritis: A diagnostic challenge"],"prefix":"10.1002","volume":"12","author":[{"given":"Tahseen Ali","family":"Al\u2010kinani","sequence":"first","affiliation":[{"name":"Coronary Care Unit Al Nasiriyah Heart Hospital  Thi Qar Iraq"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Akeel","family":"Al\u2010yacopy","sequence":"additional","affiliation":[{"name":"Coronary Care Unit Al Nasiriyah Heart Hospital  Thi Qar Iraq"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9076-8220","authenticated-orcid":false,"given":"Ahmed Qasim Mohammed","family":"Alhatemi","sequence":"additional","affiliation":[{"name":"Internal Medicine Al Nasiriyah Teaching Hospital  Thi Qar Iraq"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hashim Talib","family":"Hashim","sequence":"additional","affiliation":[{"name":"Warith Al Anbiyaa University  Karbala Iraq"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rand","family":"Abdulhussain","sequence":"additional","affiliation":[{"name":"University of Huddersfield  Huddersfield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6959-1426","authenticated-orcid":false,"given":"Ali Talib","family":"Hashim","sequence":"additional","affiliation":[{"name":"Golestan University of Medical Sciences  Gorgan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2016-310848"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2010.82"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2018.00265"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-120-11-199406010-00004"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2005.03312.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.8511"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/603171"},{"issue":"103","key":"e_1_2_12_9_1","first-page":"189","article-title":"Clinical assessment in Takayasu's arteritis: major challenges and controversies","volume":"35","author":"Direskeneli H","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1804-136"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2013.04.025"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9051","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T06:43:40Z","timestamp":1720680220000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/ccr3.9051"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9051","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"2024-01-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9051"}}