{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:07:36Z","timestamp":1753862856279,"version":"3.41.2"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>Infective endocarditis is an important differential diagnosis in patients with persistent fever and chills not responding to antibiotics and involvement of multiple organs. It can present without any specific signs such as valvular murmurs and no growth on blood cultures. Therefore, considering an echocardiography can be crucial and helpful in establishing the diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Infective endocarditis (IE), a rare disease with high mortality, arises from microbial infection affecting the heart valves and endocardium. It exhibits diverse symptoms and can involve various organs, including the brain, lungs, spleen, and liver. Diagnosis is often intricate due to its polymorphic nature, and negative blood cultures can add complexity to the diagnostic process. In this report, we present an unusual case of IE in a 53\u2010year\u2010old male farmer with multi\u2010organ involvement, including liver abscesses and pulmonary infiltration with cavities. Echocardiography showed a nodular mass attached to his bicuspid aortic valve, thus, playing a crucial role in confirming the diagnosis. This atypical manifestation highlights the necessity for increased clinical vigilance and further research to improve diagnostic approaches for uncommon IE cases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9078","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T09:41:51Z","timestamp":1720172511000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Left\u2010sided infective endocarditis presenting with pulmonary involvement and liver abscess: A case report"],"prefix":"10.1002","volume":"12","author":[{"given":"Reza","family":"Basiri","sequence":"first","affiliation":[{"name":"Lung Disease Research Center Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0426-8343","authenticated-orcid":false,"given":"Safieh","family":"Shazdehahmadi","sequence":"additional","affiliation":[{"name":"Lung Disease Research Center Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4900-6464","authenticated-orcid":false,"given":"Amir Reza","family":"Boskabadi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05153-w"},{"issue":"2","key":"e_1_2_12_3_1","first-page":"377","article-title":"Current views on infective endocarditis: changing epidemiology, improving diagnostic tools and centering the patient for up\u2010to\u2010date management","volume":"13","author":"Cimmino G","year":"2023","journal-title":"Life (Basel)"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-019-0215-0"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.10.066"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017141"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens11111220"},{"key":"e_1_2_12_8_1","unstructured":"BajuraC ProcaI RoitburtA F\u0103r\u00eem\u0103C.Pulmonary complications in infective endocarditis.2020."},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0256757"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(05)70328-7"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/CRD.0000000000000095"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-80869-y"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2020.12.009"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/idr15040045"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-023-02008-9"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12350-023-03351-y"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.6348-20"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2019.07.023"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2017.04.006"},{"issue":"4","key":"e_1_2_12_20_1","first-page":"583","article-title":"Hypervirulent Klebsiella pneumoniae infection presenting as endocarditis and liver abscess","volume":"52","author":"Hamide A","year":"2022","journal-title":"Trop Dr"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01779-09"},{"key":"e_1_2_12_22_1","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-224266","article-title":"Streptococcus anginosus endocarditis and multiple liver abscesses in a splenectomised patient","volume":"2018","author":"Finn T","year":"2018","journal-title":"BMJ Case Rep"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2019.10.007"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-022-03676-1"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540410020668"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2009.tb02454.x"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-2949-4"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46781-0"},{"issue":"4","key":"e_1_2_12_29_1","first-page":"389","article-title":"Liver abscess and infective endocarditis cases caused by Ruminococcus productus","volume":"40","author":"Sucu N","year":"2006","journal-title":"Mikrobiyol Bul"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0000000000000388"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2020.06.005"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01921"},{"key":"e_1_2_12_33_1","doi-asserted-by":"crossref","unstructured":"MichelenaHI KatanO SuriRM BaddourLM Enriquez\u2010SaranoM.Incidence of infective endocarditis in patients with bicuspid aortic valves in the community.2016.","DOI":"10.1016\/j.mayocp.2015.10.011"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951122000403"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.89.3.258"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10050551"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/23744235.2021.1925342"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T12:47:23Z","timestamp":1748350043000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/ccr3.9078"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9078","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-04-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9078"}}