{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T21:32:33Z","timestamp":1771191153624,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>When a person has both HS and beta\u2010thalassemia, their clinical symptoms tend to be less severe. This is because these two conditions have contrasting features. If the clinical symptoms and laboratory results cannot be solely attributed to hemolytic anemia, it is important to consider the possibility of another form of hemolytic anemia coexisting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>We present a 26\u2010year\u2010old woman who has been experiencing abdominal pain, jaundice, and anemia for the past 15\u2009years. Initially, she was diagnosed with gallstones and splenomegaly, but after a thorough hematology examination conducted by expert colleagues, it was discovered that she had both beta\u2010thalassemia and hereditary spherocytosis. The osmotic fragility test confirmed this diagnosis. The patient was advised to undergo both splenectomy and cholecystectomy procedures. It is worth noting that the co\u2010occurrence of these two conditions is rare.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9080","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T03:50:39Z","timestamp":1718164239000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The coincidence of beta\u2010thalassemia and hereditary spherocytosis: A case report and literature review"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1598-4288","authenticated-orcid":false,"given":"Sana","family":"Habibzadeh","sequence":"first","affiliation":[{"name":"Student Research Committee, Faculty of Medicine, Mashhad Medical Sciences Islamic Azad University  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9845-4220","authenticated-orcid":false,"given":"Majid","family":"Einakchi","sequence":"additional","affiliation":[{"name":"Department of General Surgery Imam Zaman Hospital  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7058-8597","authenticated-orcid":false,"given":"Mohammad Ebrahim","family":"Kalantari","sequence":"additional","affiliation":[{"name":"Surgical Oncology Research Center Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6947-6128","authenticated-orcid":false,"given":"Farnood","family":"Forouhar","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Mashhad Medical Sciences Islamic Azad University  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3013-1043","authenticated-orcid":false,"given":"Arefeh","family":"Ma'souminejad","sequence":"additional","affiliation":[{"name":"Surgical Oncology Research Center Mashhad University of Medical Sciences  Mashhad Iran"},{"name":"Innovative Medical Research Center, Faculty of Medicine, Mashhad Medical Sciences Islamic Azad University  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v11.i6.1349"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.12546"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.27006"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/08880019809028796"},{"issue":"2","key":"e_1_2_10_6_1","first-page":"1298","article-title":"\u03b1\u2010Thalassaemia combined with hereditary spherocytosis in the same patient","volume":"15","author":"Li X","year":"2018","journal-title":"Exp Ther Med"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2020.1846874"},{"key":"e_1_2_10_8_1","first-page":"EC09","article-title":"Combined hereditary spherocytosis and \u03b2\u2010thalassemia trait: a rare co\u2010existence","volume":"12","author":"Hb S","year":"2018","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjh.2011.36"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1993.tb03347.x"},{"issue":"9","key":"e_1_2_10_11_1","first-page":"257","article-title":"Coexistence of hereditary spherocytosis and beta\u2010thalassemia: a case report of severe hemolytic anemia in an American black","volume":"44","author":"White BP","year":"1991","journal-title":"S D J Med"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T06:46:03Z","timestamp":1720680363000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/ccr3.9080"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9080","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"2024-03-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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