{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:11Z","timestamp":1786977371256,"version":"build-2736575974"},"reference-count":6,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Key Clinical Message<\/jats:title>\n                    <jats:p>Osteopoikilosis is an asymptomatic osteosclerotic dysplasia, of autosomal dominant inheritance, which does not cause deformity or alteration in bone development, of incidental diagnosis. The differential diagnosis should be made with osteoblastic metastases, among others, especially if it is asymmetric and in patients over 50\u2009years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Osteopoikilosis is a rare benign bone disease, characterized by the appearance of bone islands in the osseous tissue, which could be confused with bone metastasis. We present the case of a 69\u2010year\u2010old man, in whom the presence of multiple punctate lesions spread throughout the skeleton was discovered after an accidental fall with a fracture of the T11 vertebral body complicated by acute osteomyelitis. The importance of this clinical case lies in the need to rule out neoplastic cause after the vertebral fracture, since osteopoikilosis is usually an incidental finding and the specific characteristics of the radiological image would avoid unnecessary interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.9191","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T18:42:21Z","timestamp":1721328141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Osteopoikilosis\u2014the incidental finding of a rare bone dysplasia: A case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5361-8099","authenticated-orcid":false,"given":"Tejera\u2010P\u00e9rez","family":"Rosa\u2010Juana","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Complejo Hospitalario Universitario Nuestra Se\u00f1ora de Candelaria  Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aguilar\u2010L\u00f3pez","family":"Ana","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Complejo Hospitalario Universitario Nuestra Se\u00f1ora de Candelaria  Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marfil\u2010Daza","family":"Julia","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Complejo Hospitalario Universitario Nuestra Se\u00f1ora de Candelaria  Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casta\u00f1o\u2010P\u00e9rez","family":"Sara","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Complejo Hospitalario Universitario Nuestra Se\u00f1ora de Candelaria  Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-023-04025-6"},{"issue":"4","key":"e_1_2_13_3_1","first-page":"273","article-title":"LEMD3: the gene responsible for bone density disorders (osteopoikilosis)","volume":"7","author":"Ben\u2010Asher E","year":"2005","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.48176\/esmj.2023.124"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20150349"},{"issue":"2","key":"e_1_2_13_6_1","article-title":"Osteopoiquilosis: reporte de un caso y revisi\u00f3n bibliogr\u00e1fica","volume":"54","author":"Alonso\u2010Escalante JC","year":"2012","journal-title":"Acta M\u00e9d Costarric"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003868"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T08:48:02Z","timestamp":1748335682000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":6,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/ccr3.9191"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9191","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9191"}}