{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:07:59Z","timestamp":1753862879905,"version":"3.41.2"},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>In the context of lymphoma, it is of paramount importance to perform subsequent Positron Emission Tomography\u2010Computed Tomography (PET\u2010CT) scans to ensure the comprehensive eradication of neoplasms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Primary renal diffuse tumors constitute less than 1% of all renal neoplasms. Among these, diffuse renal large B\u2010cell lymphoma is an exceedingly rare extranodal lymphoma. A 64\u2010year\u2010old male presented to the Department of Urology with complaints of persistent left flank discomfort for a duration of 2\u2009weeks. Additionally, he reported generalized weakness, fatigue, and symptoms indicative of lower urinary tract obstruction, such as discomfort in the left testicle and dysuria. Ultrasound imaging revealed an echogenic structure with thickened, reactive walls and a turbid fluid core, located in the left flank, proximal to the lower pole of the kidney. This structure was subsequently identified as diffuse renal large B\u2010cell lymphoma. For the diagnosis of large B\u2010cell lymphomas, it is imperative that a proficient hematopathologist performs a comprehensive examination of the tumor tissue, preferably utilizing an excisional biopsy. The categorization of lymphoma requires specialized tests such as immunohistochemistry, flow cytometry, fluorescence in\u00a0situ hybridization (FISH), and molecular testing. In instances where a renal mass is detected, healthcare professionals should consider performing a biopsy. In lymphoma cases, follow\u2010up Positron Emission Tomography\u2010Computed Tomography (PET\u2010CT) scans are crucial to confirm the complete eradication of the tumor.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9194","type":"journal-article","created":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T02:11:11Z","timestamp":1721441471000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A 64\u2010year\u2010old male with primary diffuse renal large B\u2010cell non\u2010Hodgkin lymphoma: A rare case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7335-2096","authenticated-orcid":false,"given":"Hasan","family":"Haydar","sequence":"first","affiliation":[{"name":"Faculty of Medicine Hama University  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8887-0739","authenticated-orcid":false,"given":"Mouhammed","family":"Sleiay","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Hama University  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1424-5308","authenticated-orcid":false,"given":"Hadi","family":"Alabdullah","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Hama University  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rouba","family":"Al\u2010alloush","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Hama University  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nour","family":"Al_alloush","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Hama University  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad Yasin","family":"Lutfi","sequence":"additional","affiliation":[{"name":"Urology Department Hama National Hospital  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Youssef","sequence":"additional","affiliation":[{"name":"Pathology Department Hama National Hospital  Hama Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suaad","family":"Hamsho","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Faculty of Medicine Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23589"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-226328"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2015.01.006"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-01-643569"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgu010"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.8800"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28849"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25460"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060519842049"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v10.i16.5352"},{"issue":"6","key":"e_1_2_12_12_1","first-page":"7045","article-title":"Primary renal diffuse large B\u2010cell lymphoma with central nervous system involvement: a rare case report and literature review","volume":"8","author":"Wang Y","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-234810"}],"container-title":["Clinical Case 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