{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:53:51Z","timestamp":1771462431658,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>A surgical MDT approach to high\u2010complexity surgeries can allow maximal resection in order to achieve disease control and excellent functional outcomes, as demonstrated here for a case of hidradenitis suppurativa in a patient with Crohn's disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Hidradenitis suppurativa is an autoimmune disease characterized by abscess and fistula formation with purulent discharge in intertriginous zones, and is associated with inflammatory bowel disease. We present the case of a patient with severe ongoing hidradenitis suppurativa causing osteomyelitis and affecting the perineum, on a background of Crohn's disease previously treated with panprotocolectomy and permanent ileostomy. The hidradenitis suppurativa was having a severe impact on the patient's quality of life, and she had failed to respond to conservative management. The patient opted for a radical two\u2010step procedure: first her coccyx and sacrum were removed. The second step was a radical bilateral anterior vulvectomy and posterior vaginectomy, with preservation of the uterine body and cervix. An anterolateral thigh flap was used to reconstruct the perineum. This complex procedure required the expertise of multiple surgical specialties, including plastic, general, spinal, and gynecological oncology surgeons to achieve maximal disease resection, minimizing the risk of recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9203","type":"journal-article","created":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T01:59:25Z","timestamp":1721440765000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Complex hidradenitis suppurativa on a background of long\u2010standing Crohn's disease requiring radical pelvic and perineal reconstruction: A case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2664-2437","authenticated-orcid":false,"given":"Bea Harris","family":"Forder","sequence":"first","affiliation":[{"name":"Medical Sciences Division University of Oxford  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1228-1602","authenticated-orcid":false,"given":"Sabina","family":"Nistor","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Oncology Oxford University Hospitals Foundation Trust  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Mykula","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Oxford University Hospitals Foundation Trust  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Bignell","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Oxford University Hospitals Foundation Trust  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3293-5321","authenticated-orcid":false,"given":"Hooman","family":"Soleymani\u00a0majd","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Oncology Oxford University Hospitals Foundation Trust  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0156-2"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32448-0"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.117"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2019.0891"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.08.031"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0866"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.061"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0149-1"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijwd.2021.07.008"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2012.10.013"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16749"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.09.008"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003840050159"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.10.030"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20975"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.11.018"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.15196"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2006.00559.x"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrac098"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7689"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-237669"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-252233"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T12:48:28Z","timestamp":1748350108000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/ccr3.9203"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9203","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9203"}}