{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:08:19Z","timestamp":1753862899098,"version":"3.41.2"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>The purpose of this article is to highlight that oral Kaposi's disease can be indicative of a high viral load of HIV, either in the case of primary infection or therapeutic failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>We report two cases of Kaposi Disease associated with HIV. The first case was a 30\u2010year\u2010old patient who unaware of her HIV\u2010positive status, and who was diagnosed with AIDS stage because of the biopsy revealed a gingival location of Kaposi disease. The second case was a 34\u2010year\u2010old patient who was referred to our department with a history of palatal lesion and claimed at first having no previous known medical conditions although his overall health condition seemed deteriorated. Our clinical examination was evocative of Kaposi Disease, which was confirmed by an emergency blood assessment and histological examination. Our diagnosis led us to disclose the HIV\u2010positive status of the patient and identify a progression to the AIDS stage, which allowed us to reintroduce the patient in the hospital framework. This case emphasizes the role of the oral surgeon as a key actor thanks to their knowledge of the clinical buccal manifestations of sexually transmitted infections (STI), in an era of resurgence of those conditions in vulnerable key populations.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9253","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T02:06:01Z","timestamp":1723082761000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Kaposi disease revealing HIV treatment breach: A report of two cases"],"prefix":"10.1002","volume":"12","author":[{"given":"Camille","family":"Attal","sequence":"first","affiliation":[{"name":"Oral and Dental Medicine Department Piti\u00e9 Salpetri\u00e8re Hospital, Paris Cit\u00e9 University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Demoury","sequence":"additional","affiliation":[{"name":"Oral and Dental Medicine Department Piti\u00e9 Salpetri\u00e8re Hospital, Paris Cit\u00e9 University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Reimbold","sequence":"additional","affiliation":[{"name":"Anatomy and Pathology Department Sorbonne University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurore","family":"Mensah","sequence":"additional","affiliation":[{"name":"IHP group Laboratoire D'anatomie Pathologique IHP Paris  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9raldine","family":"Lescaille","sequence":"additional","affiliation":[{"name":"Oral and Dental Medicine Department Piti\u00e9 Salpetri\u00e8re Hospital, Paris Cit\u00e9 University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9835-8275","authenticated-orcid":false,"given":"Juliette","family":"Rochefort","sequence":"additional","affiliation":[{"name":"Oral and Dental Medicine Department Piti\u00e9 Salpetri\u00e8re Hospital, Paris Cit\u00e9 University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13246208"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-9668.160041"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000601"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2012.01180.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14831"},{"key":"e_1_2_11_7_1","unstructured":"https:\/\/www.has\u2010sante.fr\/jcms\/c_2873692\/en\/biktarvy\u2010bictegravir\u2010emtricitabine\u2010tenofovir\u2010alafenamide\u2010antiretroviral\u2010combination."},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13235927"},{"issue":"6","key":"e_1_2_11_9_1","first-page":"892","article-title":"S1 guidelines for the Kaposi sarcoma","volume":"20","author":"Esser S","year":"2022","journal-title":"J Dtsch Dermatol Ges"},{"issue":"17","key":"e_1_2_11_10_1","first-page":"7488","article-title":"The treatment of Kaposi's sarcoma: present and future options, a review of the literature","volume":"23","author":"Ceccarelli M","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2991\/jegh.k.210621.001"},{"key":"e_1_2_11_12_1","unstructured":"Global AIDS.Strategy 2021\u20132026 UNAIDS.2021."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-69819-5"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1086\/533415"},{"key":"e_1_2_11_15_1","unstructured":"Quotidiano Sanit\u00e0.Update on antiviral regimens for treating and preventing HIV infection and update on early infant diagnosis of HIV WHO.2018https:\/\/www.quotidianosanita.it\/allegati\/allegato1573021.pdf"},{"issue":"6","key":"e_1_2_11_16_1","article-title":"Emergent resistance to dolutegravir among INSTI\u2010Na\u00efve patients on first\u2010line or second\u2010line antiretroviral therapy: a review of published cases. Open forum","volume":"7","author":"Cevik M","year":"2020","journal-title":"Infect Dis"},{"key":"e_1_2_11_17_1","unstructured":"https:\/\/www.ema.europa.eu\/en\/documents\/overview\/sunlenca\u2010epar\u2010medicine\u2010overview_fr.pdf."},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02937-8"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/13691058.2014.905706"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-008-9169-0"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2017.4726"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(05)70114-8"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(94)90195-3"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-250506"},{"key":"e_1_2_11_25_1","first-page":"738","article-title":"Les infections sexuellement transmissibles bact\u00e9riennes en France: situation en 2015 et \u00e9volutions r\u00e9centes","volume":"41","author":"Ndeikoundam Ngangro N","year":"2016","journal-title":"Bull Epid\u00e9miol Hebd"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T04:29:25Z","timestamp":1726288165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":24,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1002\/ccr3.9253"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9253","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"2023-08-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9253"}}