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Karyotyping and imaging studies help to detect hidden chromosomal abnormalities and anatomical differences, emphasizing their value in this context.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>A 16\u2010year\u2010old girl with absent menstruation and short stature. Further examination revealed constitutional stunting and primary amenorrhea. Karyotyping revealed a 46, XY chromosomal abnormality, whereas pelvic ultrasonography showed uterine hypoplasia and a unicornuate uterus with a rudimentary horn. After 11\u2009months of therapy, she experienced menarche and improved secondary sexual characteristics.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9318","type":"journal-article","created":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T05:19:45Z","timestamp":1723785585000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Rare case of complete gonadal dysgenesis in a female patient with primary amenorrhea and a 46XY karyotype"],"prefix":"10.1002","volume":"12","author":[{"given":"Nurbek","family":"Monolov","sequence":"first","affiliation":[{"name":"Department of Clinical and Morphological Disciplines Salymbekov University  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulbolsun","family":"Nurbekova","sequence":"additional","affiliation":[{"name":"Inpatient Department URFA Center of Radiology  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elmira","family":"Mamytova","sequence":"additional","affiliation":[{"name":"Department of Clinical and Morphological Disciplines Salymbekov University  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdurashid","family":"Unusov","sequence":"additional","affiliation":[{"name":"Gynecology Department DOC University Clinic  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meerim","family":"Osmonova","sequence":"additional","affiliation":[{"name":"Gynecology Department DOC University Clinic  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meerim","family":"Makambaeva","sequence":"additional","affiliation":[{"name":"Gynecology Department DOC University Clinic  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1007-2422","authenticated-orcid":false,"given":"Yethindra","family":"Vityala","sequence":"additional","affiliation":[{"name":"Department of Pathology International Higher School of Medicine  Bishkek Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tugolbai","family":"Tagaev","sequence":"additional","affiliation":[{"name":"Department of Hospital Internal Medicine, Occupational pathology with a course of Hematology I.K. 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