{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:07:50Z","timestamp":1753862870633,"version":"3.41.2"},"reference-count":16,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T00:00:00Z","timestamp":1724716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec><jats:title>Key Clinical Message<\/jats:title><jats:p>It is important to recognize and manage gastrointestinal symptoms in patients with BD, as they are linked to high rates of mortality and morbidity. BD can affect any part of the gastrointestinal tract, and prompt diagnosis and appropriate treatment are essential to prevent complications. Additionally, the diagnosis of BD is primarily based on clinical factors due to the lack of pathognomonic laboratory tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>Beh\u00e7et's disease (BD) is an idiopathic, chronic, and relapsing multi\u2010systemic vasculitis characterized by recurrent skin lesions and eye disease. There is no pathognomonic laboratory testing; the diagnosis is made mainly on clinical factors. BD symptoms affecting the gastrointestinal (GI) system are particularly important as they are linked to high rates of mortality and morbidity. Although ileocecal involvement is most frequently mentioned, BD can affect any part of the GI tract. There are techniques for keeping track of disease activity during treatment, but they are not ideal. We present a case of a 38\u2010year\u2010old male patient admitted to the ICU with a history of black tarry stools of 1\u2010month duration, fresh blood per rectum 5 to 7 times a day associated with fever, chills, and back and nonspecific joint pain for five days. The patient also experienced left eye episcleritis while being hospitalized, which was later confirmed to be BD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccr3.9348","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T09:00:36Z","timestamp":1724749236000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beh\u00e7et's disease presented with obscure gastrointestinal bleeding: A Palestinian case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1068-2984","authenticated-orcid":false,"given":"Afnan W. M.","family":"Jobran","sequence":"first","affiliation":[{"name":"Faculty of Medicine Al Quds University  Jerusalem Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9854-7965","authenticated-orcid":false,"given":"Abdelrhman","family":"Janem","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al Quds University  Jerusalem Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7648-0069","authenticated-orcid":false,"given":"Tareq","family":"Alhor","sequence":"additional","affiliation":[{"name":"Gastroenterology fellow Al Ahli Hospital  Hebron Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5259-145X","authenticated-orcid":false,"given":"Muhammad","family":"Idris","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al Quds University  Jerusalem Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8545-7277","authenticated-orcid":false,"given":"Mustafa","family":"Nabilsi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al Quds University  Jerusalem Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1700-8159","authenticated-orcid":false,"given":"Salam","family":"Mughrabi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al Quds University  Jerusalem Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9312-9730","authenticated-orcid":false,"given":"Aisha","family":"Alfakhry","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0812-8143","authenticated-orcid":false,"given":"Hazem","family":"Ashhab","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al Quds University  Jerusalem Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,27]]},"reference":[{"volume-title":"Treasure Island (FL): StatPearls Publishing Copyright\u00a92022","year":"2022","author":"Adil A","key":"e_1_2_12_2_1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.87.9.1175"},{"key":"e_1_2_12_4_1","first-page":"1","article-title":"Update on the diagnosis and management of Beh\u00e7et's disease","volume":"7","author":"Rokutanda R","year":"2015","journal-title":"Open Access Rheumatology: Research and Reviews"},{"issue":"4","key":"e_1_2_12_5_1","first-page":"67","article-title":"Anti\u2010Saccharomyces cerevisiae antibodies (ASCA) in Beh\u00e7et's syndrome","volume":"23","author":"Fresko I","year":"2005","journal-title":"Clin Exp Rheumatol"},{"volume-title":"StatPearls [Internet]","year":"2024","author":"Rahman S","key":"e_1_2_12_6_1"},{"issue":"335","key":"e_1_2_12_7_1","first-page":"80","article-title":"International Study Group for Beh\u00e7et's Disease. 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